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Interactions of paraoxonase-1 with pharmacologically relevant carbamates
Anita Bosak, Aljoša Bavec, Tilen Konte, Goran Šinko, Zrinka Kovarik, Marko Goličnik
Izvirni znanstveni članek
Oznake: paraoxonase-1;arylesterase activity;reversible inhibition;
Mammalian paraoxonase-1 hydrolyses a very broad spectrum of esters such as certain drugs and xenobiotics. The aim of this study was to determine whether carbamates influence the activity of recombinant PON1 (rePON1). Carbamates were selected having a variety of applications: bambuterol and physostig ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
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