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Št. zadetkov: 7
ǂThe ǂstructure and function of paraoxonase-1 and its comparison to paraoxonase-2 and -3
Ajda Taler-Verčič, Marko Goličnik, Aljoša Bavec
Pregledni znanstveni članek
Oznake: paraoxonase;lactonase;oxidative stress;
Serum paraoxonase-1 (PON1) is the most studied member of the group of paraoxonases (PONs). This enzyme possesses three enzymatic activities: lactonase, arylesterase, and paraoxonase activity. PON1 and its isoforms play an important role in drug metabolism as well as in the prevention of cardiovascul ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
ǂThe ǂremoval of time–concentration data points from progress curves improves the determination of Km
Boštjan Petrič, Marko Goličnik, Aljoša Bavec, Aljoša Bavec
Izvirni znanstveni članek
Oznake: paraoksonaza 1;dihidrokumarin;krivulje napredka;paraoxonase 1;dihydrocoumarin;progress curves;
Several approaches for determining an enzyme’s kinetic parameter Km (Michaelis constant) from progress curves have been developed in recent decades. In the present article, we compare different approaches on a set of experimental measurements of lactonase activity of paraoxonase 1 (PON1): (1) a diff ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Interactions of paraoxonase-1 with pharmacologically relevant carbamates
Anita Bosak, Aljoša Bavec, Tilen Konte, Goran Šinko, Zrinka Kovarik, Marko Goličnik
Izvirni znanstveni članek
Oznake: paraoxonase-1;arylesterase activity;reversible inhibition;
Mammalian paraoxonase-1 hydrolyses a very broad spectrum of esters such as certain drugs and xenobiotics. The aim of this study was to determine whether carbamates influence the activity of recombinant PON1 (rePON1). Carbamates were selected having a variety of applications: bambuterol and physostig ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Tresholds of blood variables obtained by receiver operating characteristic analysis for indication of fat and glycogen content in the liver of postpartum dairy cows
Ožbalt Podpečan, Petra Zrimšek, Janko Mrkun, Marko Goličnik, Anita Radovanović, Ljubomir Jovanović, I. Vujanac, Radiša Prodanović, Danijela Kirovski
Izvirni znanstveni članek
Oznake: cattle - metabolism;liver - physiology;adipose tissue;postpartum period;bovine liver;fat;glycogen;indication;
The objective was to determine optimal thresholds of blood variables that are associated withliver lipid and glycogen content in dairy cows. Liver specimens of 15 Holstein dairy cows weretaken 2 weeks postpartum (PP) and used for determination of lipid and glycogen content,respectively. Blood sample ...
Leto: 2020 Vir: Veterinarska fakulteta (UL VF)
Investigation of paraoxonase-1 genotype and enzyme-kinetic parameters in the context of cognitive impairment in Parkinson’s disease
Boštjan Petrič, Sara Redenšek, Vita Dolžan, Milica Gregorič Kramberger, Maja Trošt, Nikola Maraković, Marko Goličnik, Aljoša Bavec, Aljoša Bavec
Izvirni znanstveni članek
Oznake: Parkinsonova bolezen;kognitivne motnje;paraoksonaza 1;Parkinson disease;cognitive impairment;paraoxonase 1;
Cognitive impairment is a common non-motor symptom of Parkinson’s disease (PD), which often progresses to PD dementia. PD patients with and without dementia may differ in certain biochemical parameters, which could thus be used as biomarkers for PD dementia. The enzyme paraoxonase 1 (PON1) has previ ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Obravnava bolnikov z malignimi limfomi, Ljubljana, 25. oktober 2019
Jana Pahole Goličnik, Marko Boc
Druge monografije in druga zaključena dela
Oznake: maligni limfomi;zdravljenje;bolniki;
Obravnava bolnikov z malignimi limfomi, Ljubljana, 25. oktober 2019
Leto: 2019 Vir: Onkološki inštitut Ljubljana (OI)
Arheološki park Turške šance "Šance za zanamce"
Rok Kamnik, Marko Jaušovec, Matjaž P. Nekrep, Saša Djura Jelenko, Darja Čepin, Nejc Gonza, Aleksandra Korpič, Aneja Lah, Zala Popič, Klara Šoster, Katja Goličnik, Simon Harc, Stanislav Hozjan, Kristina Tomiek, Vid Markota, Matjaž Pongrac
Končno poročilo o rezultatih raziskav
Oznake: arheologija;domoznanstvo;turške šance;
Arheološki park Turške šance "Šance za zanamce"
Leto: 2020 Vir: Fakulteta za gradbeništvo, prometno inženirstvo in arhitekturo (UM FGPA)
Št. zadetkov: 7
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