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Zirconia-toughened alumina ceramic wear particles do not elicit inflammatory responses in human macrophages
Alessandro Alan Porporati, Yvonne Mödinger, Sarah Fischer, Sara Polajžer, Melanie Mettang, Ulrike Deisinger, Matejka Podlogar, Rihard Trebše, Nika Lovšin
Izvirni znanstveni članek
Oznake: orthopaedic implant;alumina;zirconia-toughened alumina (ZTA);nanoparticles;macrophages;cell viability;inflammation;cytokine secretion;
Ten percent of patients undergoing total hip arthroplasty (THA) require revision surgery. One of the reasons for THA are wear particles released from the implants that can activate the immune defense and cause osteolysis and failure of the joint implant. The discrepancies between reports on toxicity ...
Leto: 2023 Vir: Fakulteta za farmacijo (UL FFA)
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