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Št. zadetkov: 3
Whole-cell biopanning with a synthetic phage display library of nanobodies enabled the recovery of follicle-stimulating hormone receptor inhibitors
Ronan Crepin, Ario De Marco
Izvirni znanstveni članek
Oznake: nanobodies;GPCR proteins;FSHR;panning;pre-immune antibody library;
Antibodies are essential reagents that are increasingly used in diagnostics and therapy. Their specificity and capacity to recognize their native antigen are critical characteristics for their in vivo application. Follicle-stimulating hormone receptor is a GPCR protein regulating ovarian follicula ...
Leto: 2017 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Bacterial cytoplasm as an effective cell compartment for producing functional VHH-based affinity reagents and Camelidae IgG-like recombinant antibodies
Selma Djender, Aurelie Schneider, Anne Beugnet, Ronan Crepin, Klervi Even Desrumeaux, Chiara Romani, Sandrine Moutel, Franck Perez, Ario De Marco
Izvirni znanstveni članek
Oznake: recombinant antibodies;cytoplasmic expression;functional tags;
Bacterial cytoplasm as an effective cell compartment for producing functional VHH-based affinity reagents and Camelidae IgG-like recombinant antibodies
Leto: 2014 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Nanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts
Ronan Crepin, David Gentien, Angeline Duché, Audrey Rapinat, Cecile Reyes, Fariba Némati, Gérald Massonnet, Didier Decaudin, Selma Djender, Sandrine Moutel, Klervi Even Desrumeaux, Nathalie Cassoux, Sophie Piperno-Neumann, Sebastian Amigorena, Franck Perez, Sergio Roman-Roman, Ario De Marco
Izvirni znanstveni članek
Oznake: nanobodies;uveal melanoma;patient derived xenografts;MUC18;membrane surface biomarkers;panning;tumor polyclonality;
Monoclonal antibodies specific for biomarkers expressed on the surface of uveal melanoma (UM) cells would simplify the immune-capture and genomic characterization of heterogeneous tumor cells originated from patient derived xenografts (PDXs). Antibodies against four independent tumor antigens were i ...
Leto: 2017 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 3
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