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CCR5-mediated signaling is involved in invasion of glioblastoma cells in its microenvironment
Metka Novak, Miha Koprivnikar Krajnc, Barbara Hrastar, Barbara Breznik, Bernarda Majc, Mateja Mlinar, Ana Rotter, Andrej Porčnik, Jernej Mlakar, Katja Stare, Richard G. Pestell, Tamara Lah Turnšek
Izvirni znanstveni članek
Oznake: glioblastom;kemokini;tumorsko mikrookolje;invazija;CCL5;CCR5;chemokines;glioblastoma;invasion;maraviroc;mesenchymal stem cells;
The chemokine CCL5/RANTES is a versatile inflammatory mediator, which interacts with the receptor CCR5, promoting cancer cell interactions within the tumor microenvironment. Glioblastoma is a highly invasive tumor, in which CCL5 expression correlates with shorter patient survival. Using immunohistoc ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
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