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Št. zadetkov: 8
Integration of genomic and transcriptomic data of inbred mouse models for polygenic obesity and leanness revealed “obese” and “lean” candidate alleles in polyadenylation signals
Martin Šimon, Špela Mikec, Nicholas M. Morton, Santosh S. Atanur, Simon Horvat, Tanja Kunej
Izvirni znanstveni članek
Oznake: genetika;genomika;transkriptomika;debelost;mišji modeli;kandidatni alali;
Most mammalian genes have multiple polyadenylation (PA) sites, and alternative polyadenylation (APA) has been linked to diseases such as obesity. Studies have shown that changes in the polyadenylation signal (PAS) can influence the efficiency of cleavage and affect disease susceptibility and phenoty ...
Leto: 2024 Vir: Biotehniška fakulteta (UL BF)
Genome-wide screening for genetic variants in polyadenylation signal (PAS) sites in mouse selection lines for fatness and leanness
Martin Šimon, Špela Mikec, Nicholas M. Morton, Santosh S. Atanur, Janez Konc, Simon Horvat, Tanja Kunej
Izvirni znanstveni članek
Oznake: debelost;mišji modeli;debela linija;vitka linija;genetika;alternativna poliadenilacija;
Alternative polyadenylation (APA) determines mRNA stability, localisation, translation and protein function. Several diseases, including obesity, have been linked to APA. Studies have shown that single nucleotide polymorphisms in polyadenylation signals (PAS-SNPs) can influence APA and affect phenot ...
Leto: 2023 Vir: Biotehniška fakulteta (UL BF)
Whole genome sequencing of mouse lines divergently selected for fatness (FLI) and leanness (FHI) revealed several genetic variants as candidates for novel obesity genes
Martin Šimon, Špela Mikec, Santosh S. Atanur, Janez Konc, Nicholas M. Morton, Simon Horvat, Tanja Kunej
Izvirni znanstveni članek
Oznake: debelost;mišji modeli;genetika;genomika;kandidatni geni;
Background Analysing genomes of animal model organisms is widely used for understanding the genetic basis of complex traits and diseases, such as obesity, for which only a few mouse models exist, however, without their lean counterparts. Objective To analyse genetic differences in the unique mouse ...
Leto: 2024 Vir: Biotehniška fakulteta (UL BF)
ǂA ǂstratified transcriptomics analysis of polygenic fat and lean mouse adipose tissue identifies novel candidate obesity genes
Nicholas M. Morton, Yvonne B. Nelson, Zoi Michailidou, Emma M. Di Rollo, Lynne Ramage, Patrick W.F. Hadoke, Jonathan R. Seckl, Lutz Bunger, Simon Horvat, Christopher J. Kenyon, Donald R. Dunbar
Izvirni znanstveni članek
Oznake: molekularna genetika;debelost;geni;poligeni mišji model;
Obesity and metabolic syndrome results from a complex interaction between genetic and environmetal factors. In addition to brain-regulated processes, recent genome wide association studies have indicated that genes highly expressed in adipose tissue affect the distribution and function of fat and th ...
Leto: 2011 Vir: Biotehniška fakulteta (UL BF)
Environmental toxicants
Morton Lippmann
Ni določena
Oznake: ekologija;toksikologija;nevarne snovi;prašni delci;mineralna vlakna;izpušni plini;pesticidi;ozon;benzen;
Environmental toxicants
Leto: 2009 Vir: Fakulteta za zdravstvene vede (UM FZV)
Medicinske knjižnice v Veliki Britaniji
T.L. Morton
Izvirni znanstveni članek
Oznake:
Leto: 1973 Vir: dLib.si Digitalna knjižnica Slovenije
International study of definitions of English-language terms for suicidal behaviours
Benjamin Goodfellow, Kairi Kölves, Diego De Leo, Morton Silverman, Alan Lee Berman, John J. Mann, Ella Arensman, Keith Hawton, Michael Phillips, Lakshmi Vijayakumar
Izvirni znanstveni članek
Oznake: mnenjska raziskava;samomorilna vedenja;mednarodna raziskava;opinion survey;suicidal behaviors;international study;
International study of definitions of English-language terms for suicidal behaviours
Leto: 2019 Vir: Univerza na Primorskem (UP)
Analysis of exhaled breath to identify critically ill patients with ventilator-associated pneumonia
T. W. Felton, Waqar Ahmed, I. R. White, Pouline M. van Oort, Nicholas J. W. Rattray, C. Docherty, Jonathan Bannard-Smith, J.B. Morton, Ingeborg Welters, R. McMullan
Izvirni znanstveni članek
Oznake: breath;diagnosis;ventilator-associated pneumonia;
Ventilator-associated pneumonia commonly occurs in critically ill patients. Clinical suspicion results in overuse of antibiotics, which in turn promotes antimicrobial resistance. Detection of volatile organic compounds in the exhaled breath of critically ill patients might allow earlier detection of ...
Leto: 2023 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 8
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