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RNA toxicity in a zebrafish model for C9orf 72 ALS is abrogated by Pur-alpha and p62
Bart Swinnen
Video in druga učna gradiva
Oznake: medicine;neuroscience
A repeat expansion in the C9orf72 gene is the most frequent cause of ALS. This repeat expansion is believed to be neurotoxic because of (a combination of) direct RNA toxicity, DPR toxicity or loss of function. We aimed to investigate the role and mechanism of direct RNA toxicity in an in vivo ...
Leto: 2017 Vir: videolectures.net
Št. zadetkov: 1
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