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Št. zadetkov: 5
Priprava in karakterizacija kokristalov flukonazola
Žiga Hodnik, Danijel Kikelj
Diplomsko delo
Oznake: kokristali;interakcije;flukonazol;metode;
Priprava in karakterizacija kokristalov flukonazola
Leto: 2009 Vir: Fakulteta za farmacijo (UL FFA)
Oxidation of drugs during drug product development
Alen Gabrič, Žiga Hodnik, Stane Pajk
Pregledni znanstveni članek
Oznake: nečistoče;novi oksidativni stresorji;testiranje oksidativnega stresa;peroksidi;oxidation;peroxides;impurities;new oxidative stressors;oxidative stress testing;
Oxidation is the second most common degradation pathway for pharmaceuticals, after hydrolysis. However, in contrast to hydrolysis, oxidation is mechanistically more complex and produces a wider range of degradation products; oxidation is thus harder to control. The propensity of a drug towards oxida ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues
Nace Zidar, Sofia Montalvão, Žiga Hodnik, Dorota A. Nawrot, Aleš Žula, Janez Ilaš, Danijel Kikelj, Päivi Tammela, Lucija Peterlin-Mašič
Izvirni znanstveni članek
Oznake: marine alkaloid;Agelas;clathrodin;oroidin;pyrrole-2-aminoimidazole;antibacterial;
Marine organisms produce secondary metabolites that may be valuable for the development of novel drug leads as such and can also provide structural scaffolds for the design and synthesis of novel bioactive compounds. The marine alkaloids, clathrodin and oroidin, which were originally isolated from s ...
Leto: 2014 Vir: Fakulteta za farmacijo (UL FFA)
Minimal erythema dose determination in Holstein Friesian cattle
Jaka Jakob Hodnik, Marko Jankovec, Jožica Ježek, Žiga Krušič, Stefan Mitterhofer, Jože Starič
Izvirni znanstveni članek
Oznake: cow;ultraviolet rays;sunburn;phototesting;hair coat;cattle diseases;cattle;
Cattle on pasture are continuously exposed to solar UV radiation, which has been associated with biological effects such as sunburn, photosensitization, squamous cell carcinoma, and cutaneous vitamin D$_3$ production. The minimal erythema dose (MED) required to produce first-degree sunburn (erythema ...
Leto: 2021 Vir: Veterinarska fakulteta (UL VF)
Selective inhibition of NLRP3 inflammasome by designed peptide originating from ASC
Petra Sušjan, Duško Lainšček, Žiga Strmšek, Vesna Hodnik, Gregor Anderluh, Iva Hafner Bratkovič
Izvirni znanstveni članek
Oznake: biokemija;vnetja;krvno-možganska pregrada;peptidi;zaviralci;blood-brain barrier;inflammation;▫$IL-1\beta$▫;peptide inhibitors;
Selective inhibition of NLRP3 inflammasome by designed peptide originating from ASC
Leto: 2020 Vir: Kemijski inštitut (KI)
Št. zadetkov: 5
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