Št. zadetkov: 13
Video in druga učna gradiva
Oznake:
biology
Proteaze so encimi, ki cepijo peptidno vez in imajo pomembno vlogo tudi pri zunajcelični signalizaciji in preoblikovanju zunajceličnega matriksa. S svojim delovanjem lahko proteine na celični membrani aktivirajo, inaktivirajo ali pa kako drugače vplivajo na njihovo funkcionalnost. Cisteinski katepsi ...
Leto:
2016
Vir:
videolectures.net
Doktorska disertacija
Oznake:
receptor epidermalnega rastnega faktorja EGFR;receptorske tirozin kinaze;celična diferenciacija;migracije;poliferacije;
Leto:
2023
Vir:
Repozitorij samostojnih visokošolskih in višješolskih izobraževalnih organizacij
Izvirni znanstveni članek
Oznake:
proteoliza;proteaze;PeptideVisualizer;proteolysis;proteases;
PeptideVisualizer is an open-source software for PROTOMAP analysis, offering an intuitive graphical user interface and command-line compatibility. The software processes mass spectrometry data output from MaxQuant to visualize protein migration in polyacrylamide gel electrophoresis and sequence cove ...
Leto:
2026
Vir:
Institut Jožef Stefan (IJS)
Izvirni znanstveni članek
Oznake:
legumain;knockout mice;cellular signal transduction;
Protein phosphorylation is a common post-translational modification that plays a crucial role in cellular signal transduction. Disruptions in this process can lead to phenotypic deviations in healthy organisms. Legumain is a cysteine proteinase present in plants and animals. Legumain is involved in ...
Leto:
2026
Vir:
Institut Jožef Stefan (IJS)
Doktorska disertacija
Oznake:
zunajcelične cisteinske proteaze;membranski proteini;procesiranje;šeding;cisteinski katepsini;cisteinske proteaze;katepsin L;katepsin S;rak (medicina);tumorske celice;tumorsko mikrookolje;imunski sistem;gingipaini;bakterijske proteaze;paradontalna bolezen;disertacije;
Leto:
2020
Vir:
Repozitorij samostojnih visokošolskih in višješolskih izobraževalnih organizacij
Izvirni znanstveni članek
Oznake:
hepatocelularni karcinom;circRNAs;transkriptomske analize;hepatocellular carcinoma;transcriptomic analyses;
Circular RNAs (circRNAs) have been shown to play an important role in the pathogenesis of hepatocellular carcinoma (HCC). By implementing available transcriptomic analyses of HCC patients, we identified an upregulated circRNA hsa_circ_0062682. Stable perturbations of hsa_circ_0062682 in Huh-7 and SN ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Video in druga učna gradiva
Oznake:
biology;chemistry
**prof. dr. Marko Fonović: Proteomska identifikacija substratov cisteinskih katepsinov na površini rakavih celic**\\
Proteaze so encimi, ki cepijo peptidno vez in imajo pomembno vlogo tudi pri zunajcelični signalizaciji in preoblikovanju zunajceličnega matriksa. S svojim delovanjem lahko proteine n ...
Leto:
2016
Vir:
videolectures.net
Izvirni znanstveni članek
Oznake:
cancer;cysteine cathepsin;cathepsin L;EGFR;extracellular cleavage;resistance to TKIs;
Proteolytic activity in the tumour microenvironment is an important factor in cancer development since it can also affect intracellular signalling pathways via positive feedback loops that result in either increased tumour growth or resistance to anticancer mechanisms. In this study, we demonstrated ...
Leto:
2022
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Katarina Karničar,
Igor Drobnak,
Marko Petek,
Vasilka Magdevska,
Jaka Horvat,
Robert Vidmar,
Špela Baebler,
Ana Rotter,
Polona Jamnik,
Štefan Fujs,
Boris Turk,
Marko Fonović,
Kristina Gruden,
Gregor Kosec,
Hrvoje Petković
Izvirni znanstveni članek
Oznake:
aktinomicete;Saccharopolyspora erythraea;sekundarni metaboliti;antibiotiki;eritromicin;biosinteza;metabolno inženirstvo;proteomika;
Background
Omics approaches have significantly increased our understanding of biological systems. However, they have had limited success in explaining the dramatically increased productivity of commercially important natural products by industrial high-producing strains, such as the erythromycin-pr ...
Leto:
2016
Vir:
Nacionalni inštitut za biologijo (NIB)
Izvirni znanstveni članek
Oznake:
proteoliza;sonde na osnovi aktivnosti;papainu podobna cisteinska proteaza;transpeptidacija;zelene alge;proteolysis;activity-based probes;papain-like cysteine protease;transpeptidation;green algae;
Proteases, essential regulators of plant stress responses, remain enigmatic in their precise functional roles. By employing activity-based probes for real-time monitoring, this study aimed to delve into protease activities in Chlamydomonas reinhardtii exposed to oxidative stress induced by hydrogen ...
Leto:
2024
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)