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Št. zadetkov: 14
Proteomska identifikacija substratov cisteinskih katepsinov na površini rakavih celic
Marko Fonović
Video in druga učna gradiva
Oznake: biology
Proteaze so encimi, ki cepijo peptidno vez in imajo pomembno vlogo tudi pri zunajcelični signalizaciji in preoblikovanju zunajceličnega matriksa. S svojim delovanjem lahko proteine na celični membrani aktivirajo, inaktivirajo ali pa kako drugače vplivajo na njihovo funkcionalnost. Cisteinski katepsi ...
Leto: 2016 Vir: videolectures.net
Cathepsin cleavage of epidermal growth factor receptor (EGFR) affects signaling pathways of cancer cells
Marija Grozdanić, Marko Fonović, Boris Turk, Janko Kos
Doktorska disertacija
Oznake: receptor epidermalnega rastnega faktorja EGFR;receptorske tirozin kinaze;celična diferenciacija;migracije;poliferacije;
Leto: 2023 Vir: Repozitorij samostojnih visokošolskih in višješolskih izobraževalnih organizacij
Vloga zunajceličnih cisteinskih proteaz pri procesiranju membranskih proteinov
Katarina Korenčan, Boris Turk, Marko Fonović, Nataša Kopitar-Jerala
Doktorska disertacija
Oznake: zunajcelične cisteinske proteaze;membranski proteini;procesiranje;šeding;cisteinski katepsini;cisteinske proteaze;katepsin L;katepsin S;rak (medicina);tumorske celice;tumorsko mikrookolje;imunski sistem;gingipaini;bakterijske proteaze;paradontalna bolezen;disertacije;
Leto: 2020 Vir: Repozitorij samostojnih visokošolskih in višješolskih izobraževalnih organizacij
PeptideVisualizer
Matej Kolarič, Sara Ivanovski, Tilen Sever, Boris Turk, Marko Fonović
Izvirni znanstveni članek
Oznake: proteoliza;proteaze;PeptideVisualizer;proteolysis;proteases;
PeptideVisualizer is an open-source software for PROTOMAP analysis, offering an intuitive graphical user interface and command-line compatibility. The software processes mass spectrometry data output from MaxQuant to visualize protein migration in polyacrylamide gel electrophoresis and sequence cove ...
Leto: 2026 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Phosphorylation of YBX1 in the kidneys is altered in legumain knockout-mice
Tilen Sever, Tea Sinožić, Matej Kolarič, Boris Turk, Marko Fonović
Izvirni znanstveni članek
Oznake: legumain;knockout mice;cellular signal transduction;
Protein phosphorylation is a common post-translational modification that plays a crucial role in cellular signal transduction. Disruptions in this process can lead to phenotypic deviations in healthy organisms. Legumain is a cysteine proteinase present in plants and animals. Legumain is involved in ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Circular RNA hsa_circ_0062682 binds to YBX1 and promotes oncogenesis in hepatocellular carcinoma
Rok Razpotnik, Robert Vidmar, Marko Fonović, Damjana Rozman, Tadeja Režen, Tadeja Režen
Izvirni znanstveni članek
Oznake: hepatocelularni karcinom;circRNAs;transkriptomske analize;hepatocellular carcinoma;transcriptomic analyses;
Circular RNAs (circRNAs) have been shown to play an important role in the pathogenesis of hepatocellular carcinoma (HCC). By implementing available transcriptomic analyses of HCC patients, we identified an upregulated circRNA hsa_circ_0062682. Stable perturbations of hsa_circ_0062682 in Huh-7 and SN ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Odlični v znanosti 2016 - Naravoslovje 2. del
Nataša Ivanuš Čuček , József Györkös , Mihael Brenčič , Jernej Polajnar , Mojca Kerec Kos , Marko Fonović
Video in druga učna gradiva
Oznake: biology;chemistry
**prof. dr. Marko Fonović: Proteomska identifikacija substratov cisteinskih katepsinov na površini rakavih celic**\\ Proteaze so encimi, ki cepijo peptidno vez in imajo pomembno vlogo tudi pri zunajcelični signalizaciji in preoblikovanju zunajceličnega matriksa. S svojim delovanjem lahko proteine n ...
Leto: 2016 Vir: videolectures.net
Cathepsin L-mediated EGFR cleavage affects intracellular signalling pathways in cancer
Marija Grozdanić, Barbara Sobotič, Monika Biasizzo, Tilen Sever, Robert Vidmar, Matej Vizovišek, Boris Turk, Marko Fonović
Izvirni znanstveni članek
Oznake: cancer;cysteine cathepsin;cathepsin L;EGFR;extracellular cleavage;resistance to TKIs;
Proteolytic activity in the tumour microenvironment is an important factor in cancer development since it can also affect intracellular signalling pathways via positive feedback loops that result in either increased tumour growth or resistance to anticancer mechanisms. In this study, we demonstrated ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Proteomic and physicochemical analysis of erythrocyte membrane vesicles from fresh and frozen blood
Katarina Tomić, Sara Ivanovski, Jernej Šribar, Daša Čebulj, Samuel Žvanut, Metka Lenassi, Marko Fonović, Igor Križaj, Nina Kostevšek
Izvirni znanstveni članek
Oznake: membranski vezikli;membrane vesicles;
Erythrocyte membrane vesicles (EMVs) have emerged as promising nanocarriers for drug delivery due to their biocompatibility and immune evasion through retention of erythrocyte surface proteins. The main limitation is their dependence on freshly drawn blood, which limits batch production. Long-term s ...
Leto: 2026 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Integrated omics approaches provide strategies for rapid erythromycin yield increase in Saccharopolyspora erythraea
Katarina Karničar, Igor Drobnak, Marko Petek, Vasilka Magdevska, Jaka Horvat, Robert Vidmar, Špela Baebler, Ana Rotter, Polona Jamnik, Štefan Fujs, Boris Turk, Marko Fonović, Kristina Gruden, Gregor Kosec, Hrvoje Petković
Izvirni znanstveni članek
Oznake: aktinomicete;Saccharopolyspora erythraea;sekundarni metaboliti;antibiotiki;eritromicin;biosinteza;metabolno inženirstvo;proteomika;
Background Omics approaches have significantly increased our understanding of biological systems. However, they have had limited success in explaining the dramatically increased productivity of commercially important natural products by industrial high-producing strains, such as the erythromycin-pr ...
Leto: 2016 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 14
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