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Št. zadetkov: 2
Synthesis, antimycobacterial activity, and computational insight of novel 1,4-benzoxazin-2-one derivatives as promising candidates against multidrug-resistant mycobacterium tuberculosis
Maria Grazia Mamolo, Emanuele Carosati, Diletta Pasin, Alessandro De Logu, Gianluigi Cabiddu, Marko Jukič, Daniele Zampieri
Izvirni znanstveni članek
Oznake: antimycobacterial;benzoxazinones;cytotoxicities;dockings;menaquinone-B;minimum inhibitory concentrations;
In the search for new antitubercular agents, a series of 1,4-benzoxazinone-based compounds is designed, synthesized, and evaluated. These molecules show potent antimycobacterial activity, with a minimum inhibitory concentration between 2 and 8 μg mL−1. This interesting profile includes activity agai ...
Leto: 2025 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UM FKKT)
Targeting oxysterol-binding protein (OSBP) as a novel strategy to inhibit herpes simplex virus 2 (HSV-2) replication
Andrea Civra, Andrea Civra, Fatima Nigro, Fatima Nigro, Domiziana Porporato, Domiziana Porporato, Matteo Costantino, Elisa Bianconi, Federico Zambri, Matteo De March, Marco De Conto, Emanuele Carosati, Antonio Macchiarulo
Izvirni znanstveni članek
Oznake: broad-spectrum antiviral;cholenamide derivatives;herpes simplex virus replication;oxysterol-binding protein (OSBP);oxysterols;
Leto: 2026 Vir: Univerza v Novi Gorici (UNG)
Št. zadetkov: 2
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