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Št. zadetkov: 11
Diagnostični in prognostični pomen posttranslacijskih sprememb beljakovine tau pri nevrodegenerativnih boleznih
Andreja Emeršič, Saša Čučnik
Doktorska disertacija
Oznake: fosforiliran tau;likvor;nevrodegeneracija;Alzheimerjeva bolezen;Creutzfeldt-Jakobova bolezen;multipla skleroza;
Nevrodegenerativne bolezni so heterogena skupina bolezni z napredujočo okvaro in propadom nevronov, ki ga povezujemo s kopičenjem bolezensko spremenjenih beljakovin v živčevju. V okviru doktorskega dela smo prikazali uporabnost in pojasnjevali pomen potranslacijsko spremenjenega proteina tau kot bio ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
Serumski amiloid A kot avtoimunska tarča pri vnetnih boleznih
Andreja Emeršič, Borut Božič, Snežna Sodin-Šemrl
Diplomsko delo
Oznake: avtoimunost;amiliod A;diagnostika vnetja;avtoprotitelesa;SAA;
Serumski amiloid A kot avtoimunska tarča pri vnetnih boleznih
Leto: 2011 Vir: Fakulteta za farmacijo (UL FFA)
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant pathologies
Andreja Emeršič, Andreja Emeršič, Nicholas J. Ashton, Agathe Vrillon, Juan Lantero-Rodriguez, Jernej Mlakar, Milica Gregorič Kramberger, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Maciej Dulewicz, Maciej Dulewicz, Jörg Hanrieder, Jörg Hanrieder, Uroš Rot, Saša Čučnik
Izvirni znanstveni članek
Oznake: Alzheimer's disease;Creutzfeldt–Jakob disease;cerebrospinal fluid;concomitant pathology;neuropathology;phosphorylated tau;p-tau181;p-tau217;p-tau231;
Introduction: The established cerebrospinal fluid (CSF) phosphorylated tau181 (p-tau181) may not reliably reflect concomitant Alzheimer's disease (AD) and primary age-related tauopathy (PART) found in Creutzfeldt-Jakob disease (CJD) at autopsy. Methods: We investigated CSF N-terminal p-tau181, p-tau ...
Leto: 2024 Vir: Repozitorij Univerze v Ljubljani (RUL)
Genetic polymorphisms in oxidative stress and inflammatory pathways as potential biomarkers in Alzheimer’s Disease and dementia
David Vogrinc, Milica Gregorič Kramberger, Andreja Emeršič, Saša Čučnik, Katja Goričar, Vita Dolžan, Vita Dolžan
Izvirni znanstveni članek
Oznake: Alzheimerjeva bolezen;oksidativni stres;vnetje;Alzheimer’s disease;oxidative stress;inflammation;
Oxidative stress and neuroinflammation are important processes involved in Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Numerous risk factors, including genetic background, can affect the complex interplay between those mechanisms in the aging brain and can also affect typical AD ha ...
Leto: 2023 Vir: Repozitorij Univerze v Ljubljani (RUL)
The Association of Selected GWAS reported AD risk loci with CSF biomarker levels and cognitive decline in Slovenian patients
David Vogrinc, Milica Gregorič Kramberger, Andreja Emeršič, Saša Čučnik, Katja Goričar, Vita Dolžan, Vita Dolžan
Izvirni znanstveni članek
Oznake: Alzheimer's disease;mild cognitive impairment;polymorphism;biomarker;
Alzheimer’s disease (AD) is the most common neurodegenerative disease, with a complex genetic background. Apart from rare, familial cases, a combination of multiple risk loci contributes to the susceptibility of the disease. Genome-wide association studies (GWAS) have identified numerous AD risk loc ...
Leto: 2023 Vir: Repozitorij Univerze v Ljubljani (RUL)
Genetic variability of incretin receptors affects the occurrence of neurodegenerative diseases and their characteristics
David Vogrinc, Sara Redenšek, Tanja Blagus, Maja Trošt, Milica Gregorič Kramberger, Andreja Emeršič, Saša Čučnik, Katja Goričar, Vita Dolžan, Vita Dolžan
Izvirni znanstveni članek
Oznake: Alzheimer's disease;biomarker;glucagon-like peptide 1 receptor;glucose-dependent insulinotropic polypeptide;Parkinson's disease;polymorphism;
Background: Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common neurodegenerative diseases. Their treatment options are rather limited, and no neuroprotective or disease-modifying treatments are available. Anti-diabetic drugs, such as glucagon-like peptide 1 (GLP-1) and glucose ...
Leto: 2024 Vir: Repozitorij Univerze v Ljubljani (RUL)
Prognostic value of kappa free light chain index in patients with primary progressive multiple sclerosis
Martin Schmidauer, Klaus Berek, Michael Auer, Gabriel Bsteh, Paola Cavalla, Franziska Di Pauli, Massimiliano Di Filippo, Florian Deisenhammer, Andreja Emeršič, Uroš Rot
Izvirni znanstveni članek
Oznake: cerebrospinal fluid;kappa free light chain;multiple sclerosis;primary progressive;prognostic biomarker;
Background: The kappa free light chain (κ-FLC) index is a well-established biomarker in multiple sclerosis (MS). While the prognostic value of the κ-FLC index has been demonstrated in early relapsing-remitting MS, its prognostic value in primary progressive MS (PPMS) has not yet been investigated. M ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Diagnostic value of kappa free light chain index in patients with primary progressive multiple sclerosis
Harald Hegen, Harald Hegen, Klaus Berek, Paola Cavalla, Mikael Christiansen, Andreja Emeršič, Massimiliano Di Filippo, Lorenzo Gaetani, Michaela Hassler, Cyra Leurs, Uroš Rot
Izvirni znanstveni članek
Oznake: kappa free light chain index;diagnostics;patients;multiple sclerosis;
Background: Kappa free light chains (κ-FLC) in the cerebrospinal fluid (CSF) are an emerging biomarker in multiple sclerosis (MS). Objective: To investigate whether κ-FLC index has similar diagnostic value in patients with primary progressive multiple sclerosis (PPMS) compared to oligoclonal bands ( ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer’s disease neuropathology
Przemyslaw R. Kac, Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay R. Varma, Milica Gregorič Kramberger, Saša Čučnik, Uroš Rot
Izvirni znanstveni članek
Oznake: plasma p-tau212;diagnostics;Alzheimer disease;neuropathology;
Blood phosphorylated tau (p-tau) biomarkers, including p-tau217, show high associations with Alzheimer’s disease (AD) neuropathologic change and clinical stage. Certain plasma p-tau217 assays recognize tau forms phosphorylated additionally at threonine-212, but the contribution of p-tau212 alone to ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Alterations in immunophenotype and metabolic profile of mononuclear cells during follow up in children with multisystem inflammatory syndrome (MIS-C)
Andreja Nataša Kopitar, Jernej Repas, Larisa Janžič, Maša Bizjak, Tina Vesel, Nina Emeršič, Mojca Zajc Avramovič, Alojz Ihan, Tadej Avčin, Mojca Pavlin
Izvirni znanstveni članek
Oznake: MIS-C;biomarkerji;metabolizem;B limfociti;T limfociti;monociti;aktivacija limfocitov;dendritske celice;biomarkers;metabolism;B lymphocytes;T lymphocytes;monocytes;lymphocyte activation;dendritic cells;
Alterations in immunophenotype and metabolic profile of mononuclear cells during follow up in children with multisystem inflammatory syndrome (MIS-C)
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 11
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