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Vpliv sestave formulacij in procesnih pogojev na fizikalne lastnosti liofiliziranih nanokristalov paliperidon palmitata
Ula Savšek, Julijana Kristl, Wolfgang Frieß
Magistrsko delo
Oznake: freeze-drying lyophilisation freeze-thawing high-pressure homogenization drug nanocrystals paliperidone palmitate physical stability;
A vital problem that limits the use of drug nanocrystals in pharmaceutics is their physical instability. Freeze-drying is known to be an excellent technique to improve long-term stability of colloidal systems. But still, except of empirical principles, there is little known about the mutual dependen ...
Leto: 2018 Vir: Fakulteta za farmacijo (UL FFA)
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