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Št. zadetkov: 2
Microbial genetic variation impacts host eco-immunological strategies and microparasite fitness in Lyme borreliae-reptile system
Tristan A. Nowak, Carly Fernandes, Jill Malfetano, Erica Lasek-Nesselquist, Matthew Combs, Klemen Strle, Russell L. Burke, Yi-Pin Lin
Izvirni znanstveni članek
Oznake: Lyme disease;borrelia;tolerance;resistance;genetic variation;
Tolerance and resistance are two host eco-immunological strategies in response to microparasite invasion. In the strategy of “resistance”, host responses are induced to decrease microparasite replication while the “tolerance” strategy allows hosts coexistence with microparasites by minimizing respon ...
Leto: 2024 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Phylogenomic diversity elucidates mechanistic insights into Lyme borreliae - host association
Matthew Combs, Ashley L. Marcinkiewicz, Alan P. Dupuis, April D. Davis, Patricia Lederman, Tristan A. Nowak, Jessica L. Stout, Klemen Strle, Volker Fingerle, Gabriele Margos
Izvirni znanstveni članek
Oznake: host association;Borrelia;complement;phylogenomics;plasmid diversity;
Host association—the selective adaptation of pathogens to specific host species—evolves through constant interactions between host and pathogens, leaving a lot yet to be discovered on immunological mechanisms and genomic determinants. The causative agents of Lyme disease (LD) are spirochete bacteria ...
Leto: 2022 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 2
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