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Št. zadetkov: 3
Targeting the NO-sGC-cGMP pathway
Tine Bajec, Gregor Poglajen
Pregledni znanstveni članek
Oznake: heart failure;soluble guanylate cyclase stimulators;vericiguat;
The recent advancements in the medical management of patients with chronic heart failure with reduced ejection fraction (HFrEF) is the soluble guanylate cyclase (sGC) stimulator, vericiguat. Clinical trials have demonstrated that vericiguat effectively lowers plasma levels of NT-proBNP and reduces t ...
Leto: 2025 Vir: Repozitorij Univerze v Ljubljani (RUL)
Biomarkers and genetic determinants of cardiac sarcoidosis
Tine Bajec, Matevž Harlander, Nadja Koren, Mahwash Kassi, Gregor Poglajen, Gregor Poglajen
Pregledni znanstveni članek
Oznake: biomarker;genetics;heart;sarcoidosis;therapy;
Sarcoidosis is a systemic disorder driven by genetic predisposition, environmental exposures, and immune dysregulation, resulting in the formation of noncaseating granulomas across multiple organs. In cardiac sarcoidosis (CS), immune cell infiltration of the myocardium, epicardium, and endocardium m ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Vericiguat Therapy Is Associated with Reverse Myocardial Remodeling in Chronic Heart Failure with Reduced Ejection Fraction
Tine Bajec, Neža Žorž, Sabina Ugovšek, Gregor Zemljič, Andraž Cerar, Sabina Frljak, Renata Okrajšek, Petra Girandon Sušanj, Miran Šebeštjen, Bojan Vrtovec, Gregor Poglajen
Izvirni znanstveni članek
Oznake: heart failure;myocardial reverse remodeling;soluble guanylate cyclase stimulator;
Background and aims: Vericiguat lowers cardiovascular death or heart-failure hospitalization in recently worsened heart failure with reduced ejection fraction (HFrEF), but its effects on cardiac remodeling are less well characterized. Our aim was to evaluate whether the addition of vericiguat to gui ...
Leto: 2026 Vir: Repozitorij Univerze v Ljubljani (RUL)
Št. zadetkov: 3
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