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Št. zadetkov: 3
Sodium-glucose co-transporter-2 inhibitors in Type 1 Diabetes
Tim Hropot, Tadej Battelino, Klemen Dovč
Pregledni znanstveni članek
Oznake: pediatrija;sladkorna bolezen tipa 1;kontrola glukoze;
Background: With recent developments in diabetes technology, attaining adequate glucose control is more achievable than ever. Despite these improvements, a significant proportion of individuals with type 1 diabetes do not reach recommended glycaemic goals. Sodium-glucose co-transporter-2 (SGLT2) inh ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Postprandial time in tight range with faster insulin aspart compared with standard insulin aspart in youth with type 1 diabetes using automated insulin delivery
Klemen Dovč, Charles Spanbauer, Eleonora Chiarle, Nataša Bratina, Elke Fröhlich-Reiterer, Nejka Potočnik, Dessi P. Zaharieva, Tim Hropot, Maria Fritsch, Peter Calhoun, Tadej Battelino
Izvirni znanstveni članek
Oznake: postprandial time in tight;range standard insulin aspart in youth with type 1;automated insulin delivery;
Aims The aim of this study was to assess postprandial glycaemic outcomes using automated insulin delivery with faster acting insulin aspart (FIA) or standard insulin aspart (SIA) over 4 weeks in youth (aged 10–18 years) with type 1 diabetes. Materials and Methods We undertook a secondary analysis of ...
Leto: 2025 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Diverse inhibitors of de novo purine synthesis promote AICAR-induced AMPK activation and glucose uptake in L6 myotubes
Klemen Dolinar, Katarina Miš, Katja Šopar, Mateja Šutar, Meta Božič, Matic Kolar, Tim Hropot, Pablo Miguel Garcia-Roves, Alexander V. Chibalin, Sergej Pirkmajer, Sergej Pirkmajer
Izvirni znanstveni članek
Oznake: AMP‐activated protein kinase (AMPK);folate metabolism;glucose uptake;insulin signaling;purine metabolism;skeletal muscle cells;
Methotrexate, an immunosuppressant and anticancer drug, promotes glucose uptake and lipid oxidation in skeletal muscle via activation of AMP-activated protein kinase (AMPK). Methotrexate promotes AMPK activation by inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide (ZMP) formyltransferase/inos ...
Leto: 2025 Vir: Repozitorij Univerze v Ljubljani (RUL)
Št. zadetkov: 3
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