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Št. zadetkov: 2
Identification of potential biomarkers for colorectal cancer in a mouse model using proteomics approaches
Tea Sinožić
Raziskovalni podatki
Oznake: extracellular matrix;decellularization;proteomics;stool biomarker;colorectal cancer;AOM/DSS;mouse model;
Early inflammation-driven tumorigenesis causes significant remodeling of the colonic extracellular matrix, making its proteomic composition an underexplored source of biomarker candidates. In this study, we characterized the proteomes of healthy and cancerous decellularized mouse colons and compared ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Phosphorylation of YBX1 in the kidneys is altered in legumain knockout-mice
Tilen Sever, Tea Sinožić, Matej Kolarič, Boris Turk, Marko Fonović
Izvirni znanstveni članek
Oznake: legumain;knockout mice;cellular signal transduction;
Protein phosphorylation is a common post-translational modification that plays a crucial role in cellular signal transduction. Disruptions in this process can lead to phenotypic deviations in healthy organisms. Legumain is a cysteine proteinase present in plants and animals. Legumain is involved in ...
Leto: 2026 Vir: Institut Jožef Stefan (IJS)
Št. zadetkov: 2
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