Št. zadetkov: 11
Pregledni znanstveni članek
Oznake:
single-cell landscape;bladder pain syndrome;high throughput;immune cells;interstitial cystitis;urothelial cells;
Objective: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory bladder disorder with unknown aetiology and limited treatment options. Single-cell RNA-sequencing (scRNA-seq) has provided unprecedented insights into cellular heterogeneity in IC/BPS. This review summarizes re ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
apoptosis;cyclophosphamide;differentiation;injury;proliferation;urinary bladder;urothelium;vitamin A;
Vitamin A (VitA) is an essential nutrient, affecting many cell functions, such as proliferation, apoptosis, and differentiation, all of which are important for the regeneration of various tissues. In this study, we investigated the effects of a VitA-enriched diet on the regeneration of the urotheliu ...
Leto:
2025
Vir:
Medicinska fakulteta (UL MF)
Magistrsko delo
Oznake:
gigantocelični arteritis;vzorec seruma;metoda hkratne analize;različni analiti;biopsija temporalne arterije;zdravljenje gigantoceličnega arteritisa;
Biološki označevalci pomembni pri spremljanju bolnikov z gigantoceličnim arteritisom
Leto:
2015
Vir:
Fakulteta za farmacijo (UL FFA)
Izvirni znanstveni članek
Oznake:
interstitial cystitis;inflammation;RNA sequencing;
Animal models are invaluable in the research of the pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic aseptic urinary bladder disease of unknown etiology that primarily affects women. Here, a mouse model of IC/BPS was induced with multiple low-dose cyclophosphamide ( ...
Leto:
2023
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
interstitial cystitis;bladder pain syndrome;therapeutic approaches;
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a multifactorial, chronic bladder disorder with limited therapeutic options currently available. The present review provides an extensive overview of therapeutic approaches used in in vitro, ex vivo, and in vivo experimental models of IC/BPS. P ...
Leto:
2021
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
revmatoidni artritis;sistemski eritematozni lupus;sekvenciranje RNA;rheumatoid arthritis;systemic lupus erythematosus;RNA sequencing;
Single cell RNA sequencing (scRNA-seq) represents a new large scale and high throughput technique allowing analysis of the whole transcriptome at the resolution of an individual cell. It has emerged as an imperative method in life science research, uncovering complex cellular networks and providing ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Doktorska disertacija
Oznake:
systemic vasculitis;autoantibodies;cell and molecular markers;
Giant cell arteritis and immunoglobulin A vasculitis represent a group of chronic rheumatic inflammatory diseases that are categorized as primary systemic vasculitides. They are associated with increased morbidity and earlier mortality as a result of severe cardiovascular complications and long-term ...
Leto:
2020
Vir:
Fakulteta za farmacijo (UL FFA)
Izvirni znanstveni članek
Oznake:
interstitial cystitis;bladder pain syndrome;urothelial cells;
Urothelial cells of the urinary bladder play a critical role in the development and progression of interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic and debilitating inflammatory disease. Given the lack of data on the exact phenotype and function of urothelial cells in an inflammatory ...
Leto:
2022
Vir:
Medicinska fakulteta (UL MF)
Pregledni znanstveni članek
Oznake:
bladder cancer;chronic inflammation;dietary sugar;hyperglycaemia;lifestyle strategies;therapeutic approaches;
High dietary sugar intake has emerged as a key modulator of systemic inflammation and metabolic dysregulation, both of which are associated with an increased risk of several chronic diseases, including cancer. Although bladder cancer is primarily driven by factors such as smoking and occupational ex ...
Leto:
2026
Vir:
Medicinska fakulteta (UL MF)
Izvirni znanstveni članek
Oznake:
systemic sclerosis;monocytes;autoantibodies;
Monocytes are known to be implicated in the pathogenesis of systemic sclerosis (SSc), as they exert prominent migratory, adhesive, and chemotactic properties. The aim of our study was to characterize the surface expression of adhesion/chemotactic molecules (CD62L, CD11b, CCR2, CCR5) on the SSc monoc ...
Leto:
2022
Vir:
Fakulteta za farmacijo (UL FFA)