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Št. zadetkov: 4
Defining bath ankylosing spondylitis disease activity index cut-off values for disease activity states in a multinational european cohort of patients with axial spondyloarthritis
Stylianos Georgiadis, Stylianos Georgiadis, Lykke Midtbøll Ørnbjerg, Brigitte Michelsen, Tore K. Kvien, Žiga Rotar, Katja Perdan-Pirkmajer
Izvirni znanstveni članek
Oznake: disease activity states;ankylosing spondylitis;axial spondyloarthritis;multinational European cohort;
Objective: The Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is widely used for assessing disease activity in patients with axial spondyloarthritis (axSpA), particularly in settings where markers of inflammation are unavailable. As no consensus on BASDAI cut-off values exists for disea ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Challenge of missing data in observational studies
Stylianos Georgiadis, Stylianos Georgiadis, Marion Pons, Simon Horskjær Rasmussen, Merete Lund Hetland, Louise Linde, Daniela Di Giuseppe, Brigitte Michelsen, Johan Karlsson Wallman, Tor Olofsson, Jakub Závada, Žiga Rotar, Katja Perdan-Pirkmajer
Izvirni znanstveni članek
Oznake: axial spondyloarthritis;epidemiology;interleukin-17;tumour necrosis factor inhibitors;
Objectives: We aimed to compare various methods for imputing disease activity in longitudinally collected observational data of patients with axial spondyloarthritis (axSpA). Methods: We conducted a simulation study on data from 8583 axSpA patients from ten European registries. Disease activity was ...
Leto: 2025 Vir: Repozitorij Univerze v Ljubljani (RUL)
Interchangeability of patient pain, fatigue and global scores in patients with spondyloarthritis
Stylianos Georgiadis, Stylianos Georgiadis, Daniela Di Giuseppe, Almut Scherer, Merete Lund Hetland, Gareth T. Jones, Bente Glintborg, Anne Gitte Loft, Johan Karlsson Wallman, Brigitte Michelsen, Eirik Klami Kristianslund, Žiga Rotar, Matija Tomšič
Izvirni znanstveni članek
Oznake: missing data;patient reported outcomes;registry data;single imputation;spondyloarthritis;
Background: To investigate a patient-level single imputation approach for patient reported outcomes (PROs) that express similar contents or associated PROs, where a PRO whose value is missing at a particular timepoint is substituted by another PRO whose value is available at the same timepoint. Meth ...
Leto: 2025 Vir: Repozitorij Univerze v Ljubljani (RUL)
Handling of missing component information for common composite score outcomes used in axial spondyloarthritis research when complete-case analysis is unbiased
Christos Polysopoulos, Stylianos Georgiadis, Lykke Midtbøll Ørnbjerg, Almut Scherer, Daniela Di Giuseppe, Merete Lund Hetland, Michael John Nissen, Gareth T. Jones, Bente Glintborg, Anne Gitte Loft, Katja Perdan-Pirkmajer, Žiga Rotar
Izvirni znanstveni članek
Oznake: axial spondyloarthritis;complete-case analysis;composite score;missing components;multiple imputation;aksialni spondiloartritis;analiza celotnega primera;sestavljena ocena;manjkajoče komponente;večkratna imputacija;
Background: Observational data on composite scores often comes with missing component information. When a complete-case (CC) analysis of composite scores is unbiased, preferable approaches of dealing with missing component information should also be unbiased and provide a more precise estimate. We a ...
Leto: 2025 Vir: Repozitorij Univerze v Ljubljani (RUL)
Št. zadetkov: 4
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