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Št. zadetkov: 3
ǂA ǂsystematic review of the development and application of home cage monitoring in laboratory mice and rats
Pia Kahnau, Paul Mieske, Jenny Wilzopolski, Otto Kalliokoski, Silvia Mandillo, Sabine M. Hölter, Vootele Voikar, Adriana Amfim, Sylvia Badurek, Aleksandra Bartelik, Maša Čater
Izvirni znanstveni članek
Oznake: laboratorijske živali;miši;podgane;načelo 3R;izboljšanje pogojev;dobrobit živali;
Background Traditionally, in biomedical animal research, laboratory rodents are individually examined in test apparatuses outside of their home cages at selected time points. However, the outcome of such tests can be influenced by various factors and valuable information may be missed when the anim ...
Leto: 2023 Vir: Biotehniška fakulteta (UL BF)
On the importance of including both sexes in animal studies – insights from home-cage monitoring
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco
Izvirni znanstveni članek
Oznake: monitoring v domači kletki;vpliv spola;sex differences;animal studies;animal research;preclinical research;biomedical research;behaviour;home-cage monitoring;
A review of behavioural studies using home-cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of b ...
Leto: 2026 Vir: Biotehniška fakulteta (UL BF)
Critical uncertainties in preclinical research
Indrek Heinla, Vootele Voikar, Hilary Gates, Rasneer Sonia Bains, Sara Wells, Silvia Mandillo, Maša Čater, Kristi Kukk, Lars Lewejohann, Dragan Hrnčić, Daniela Duarte-Domingues, Philipp Villiger, Leonardo Restivo, Sabine M. Hölter
Kratki znanstveni prispevek
Oznake: poskusne živali;znanstvene raziskave;etika;tehnologija;zaupanje v znanost;new approach methodologies;animal research;strategic foresight;scenarios;trust in science;competitiveness;
Animal use in preclinical research is facing growing scientific, ethical and political scrutiny in Europe. Researchers are increasingly required to justify in vivo studies and are urged to replace them with New Approach Methodologies (NAMs), even where these are not yet fit for purpose. In response ...
Leto: 2026 Vir: Biotehniška fakulteta (UL BF)
Št. zadetkov: 3
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