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Št. zadetkov: 4
Identification of new DR5 agonistic nanobodies and generation of multivalent nanobody constructs for cancer treatment
Golnaz Sadeghnezhad, Ema Romão, Robert Alvin Bernedo-Navarro, Sam Massa, Khosro Khajeh, Serge Muyldermans, Sadegh Hassania
Izvirni znanstveni članek
Oznake: death receptor 5;nanobodies;TRAIL;cancer therapy;apoptosis;
Identification of New DR5 Agonistic Nanobodies and Generation of Multivalent Nanobody Constructs for Cancer Treatment
Leto: 2019 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Structural basis for the specific neutralization of Stx2a with a camelid single domain antibody fragment
Robert Alvin Bernedo-Navarro, Ema Romão, Tomomasa Yano, Joar Pinto, Henri De Greve, Yann Sterckx, Serge Muyldermans
Izvirni znanstveni članek
Oznake: Shiga toxins;nanobodies;Stx2;neutralizers;
Structural basis for the specific neutralization of Stx2a with a camelid single domain antibody fragment
Leto: 2018 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
In vitro functional validation of an anti-FREM2 nanobody for glioblastoma cell targeting
Gloria Krapež, Neja Zupanec, Alja Zottel, Mojca Katrašnik, Ana Kump, Jernej Šribar, Igor Križaj, Jure Stojan, Rok Romih, Gregor Bajc, Matej Butala, Serge Muyldermans, Ivana Jovchevska, Ivana Jovchevska
Izvirni znanstveni članek
Oznake: brain cancer;membrane-bound protein;cytotoxicity;molecular tool;subcellular localization;
Background/Objectives: Glioblastomas are the most common brain malignancies. Despite the implementation of multimodal therapy, patient life expectancy after diagnosis is barely 12 to 18 months. Glioblastomas are highly heterogeneous at the genetic and epigenetic level and comprise multiple different ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
TRIM28 and [beta]-actin identified via nanobody-based reverse proteomics approach as possible human glioblastoma biomarkers
Ivana Jovchevska, Neja Zupanec, Nina Kočevar, Daniela Cesselli, Neža Podergajs, Clara Limbäck-Stokin, Michael P. Myers, Serge Muyldermans, Gholamreza Hassanzadeh Ghassabeh, Helena Motaln, Maria Elisabetta Ruaro, Evgenia Bourkoula, Tamara Lah Turnšek, Radovan Komel
Izvirni znanstveni članek
Oznake: malignant gliomas;cancer stem cells;nanobodies;
Malignant gliomas are among the rarest brain tumours, and they have the worst prognosis. Grade IV astrocytoma, known as glioblastoma multiforme (GBM), is a highly lethal disease where the standard therapies of surgery, followed by radiation and chemotherapy, cannot significantly prolong the life exp ...
Leto: 2014 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 4
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