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Št. zadetkov: 5
Silica-coated SPIONs induce ferroptosis in endothelial cells while oleic acid mitigates their cytotoxic effects
Neža Repar, Saša Kupčič, Sara Michelini, Eva Jarc, Ana Kump, Matej Hočevar, Slavko Kralj, Toni Petan, Damjana Drobne
Izvirni znanstveni članek
Oznake: SPION;oleic acid;GPX4;ROS;ferroptosis;lipid peroxidation;
Purpose: Induction of ferroptosis, a form of cell death driven by iron-dependent lipid peroxidation, holds promise as a novel cancer therapy. Superparamagnetic iron oxide nanoparticles (SPIONs) have been proven able to induce ferroptosis in tumour cells, while their effects on non-cancerous cells re ...
Leto: 2025 Vir: Biotehniška fakulteta (UL BF)
Heterogeneity of lipopolysaccharide as source of variability in bioassays and lps-binding proteins as remedy
Alexandra C. Fux, Cristiane Casonato Melo, Sara Michelini, Benjamin J. Swartzwelter, Andreas Neusch, Paola Italiani, Martin Himly
Pregledni znanstveni članek
Oznake: endotoxin;lipid A;immunology;detection;low endotoxin recovery;LPS-binding molecules;
Lipopolysaccharide (LPS), also referred to as endotoxin, is the major component of Gram-negative bacteria’s outer cell wall. It is one of the main types of pathogen-associated molecular patterns (PAMPs) that are known to elicit severe immune reactions in the event of a pathogen trespassing the epith ...
Leto: 2023 Vir: Biotehniška fakulteta (UL BF)
Pulmonary hazards of nanoplastic particles: a study using polystyrene in in vitro models of the alveolar and bronchial epithelium
Sara Michelini, Safaa Mawas, Ema Kurešepi, Katarina Šimunović, Neža Repar, Barbara Šetina, Ines Mandić-Mulec, Andreja Erman, Damjana Drobne
Izvirni znanstveni članek
Oznake: nanoplastika;polistiren;dihala;alveole;bronhiji;celične linije;citotoksičnost;nanoplastic;surfactant protein;mucin;lamellar body;A549;Calu-3;polystyrene;alveoli;bronchi;transwells;
Background Nanoplastics (NPs) are released into the environment through the degradation of plastic objects, leading to human exposure. Due to their small size, concerns have been raised about the potential hazards to the respiratory tract, as ultrafine and nanoparticles are known to penetrate till t ...
Leto: 2025 Vir: Biotehniška fakulteta (UL BF)
Gold nanoparticles (AuNPs) impair LPS-driven immune responses by promoting a tolerogenic-like dendritic cell phenotype with altered endosomal structures
Sara Michelini, Francesco Barbero, Alessandra Prinelli, Philip Steiner, Richard Weiss, Thomas Verwanger, Ancuela Andosch, Ursula Lütz-Meindl, Victor F. Puntes, Damjana Drobne, Albert Duschl, Jutta Horejs-Hoeck
Izvirni znanstveni članek
Oznake: nanomateriali;nanoznanosti;imunski sistem;
Dendritic cells (DCs) shape immune responses by influencing T-cell activation. Thus, they are considered both an interesting model for studying nano-immune interactions and a promising target for nano-based biomedical applications. However, the accentuated ability of nanoparticles (NPs) to interact ...
Leto: 2021 Vir: Biotehniška fakulteta (UL BF)
Inflammatory, oxidative stress and small cellular particle response in HUVEC induced by debris from endoprosthesis processing
Zala Jan, Matej Hočevar, Veno Kononenko, Sara Michelini, Neža Repar, Maja Caf, Monika Jenko, Veronika Kralj-Iglič, Boštjan Kocjančič, Drago Dolinar, Slavko Kralj, Darko Makovec, Aleš Iglič, Damjana Drobne
Izvirni znanstveni članek
Oznake: endoprosthesis failure;corundum;cytokines;reactive oxygen species;lipid droplets;
Inflammatory, oxidative stress and small cellular particle response in HUVEC induced by debris from endoprosthesis processing
Leto: 2023 Vir: Fakulteta za elektrotehniko (UL FE)
Št. zadetkov: 5
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