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Št. zadetkov: 4
Computational design and characterization of nanobody-derived peptides that stabilize the active conformation of the [beta] [sub] 2-adrenergic receptor ([beta] [sub] 2-AR)
Milan Sencanski, Sanja Glisic, Nevena Veljkovic, Marko Šnajder, Nataša Poklar Ulrih, Janez Mavri, Milka Vrecl
Izvirni znanstveni članek
Oznake: nanotelesa;mimetiki;adrenergični beta receptorji;
This study aimed to design and functionally characterize peptide mimetics of the nanobody (Nb) related to the β2-adrenergic receptor (β2-AR) (nanobody-derived peptide, NDP). We postulated that the computationally derived and optimized complementarity-determining region 3 (CDR3) of Nb is sufficient f ...
Leto: 2019 Vir: Biotehniška fakulteta (UL BF)
Critical impact of different conserved endoplasmic retention mofits and dopamine receptor interacting proteins (DRIPs) on intracellular localization and trafficking of the D2 dopamine receptor (D2-R) isoforms
Kaja Blagotinšek Cokan, Maša Mavri, Catrin Rutland, Sanja Glisic, Milan Sencanski, Milka Vrecl, Valentina Kubale
Pregledni znanstveni članek
Oznake: D$_2$ dopamine receptor;intracellular trafficking;endoplasmic reticulum;retention motifs;ICL3;interacting partners;
The type 2 dopamine receptor D2 (D2-R), member of the G protein-coupled receptor (GPCR) superfamily, exists in two isoforms, short (D2S-R) and long (D2L-R). They differ by an additional 29 amino acids (AA) in the third cytoplasmic loop (ICL3) of the D2L-R. These isoforms differ in their intracellula ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis
Maša Mavri, Sanja Glisic, Milan Sencanski, Milka Vrecl, Mette Marie Rosenklide, Katja Spiess, Valentina Kubale
Izvirni znanstveni članek
Oznake: Herpesvirus 4;human;Dynamins;Caveolins;beta-Arrestins;
Background: The viral G protein-coupled receptor (vGPCR) BILF1 encoded by the Epstein-Barr virus (EBV) is an oncogene and immunoevasin and can downregulate MHC-I molecules at the surface of infected cells. MHC-I downregulation, which presumably occurs through co-internalization with EBV-BILF1, is pr ...
Leto: 2023 Vir: Veterinarska fakulteta (UL VF)
Inhibitory potential of boscalid and abamectin towards acetylcholinesterase and butyrylcholinesterase
Biljana Arsić, Stefan Petrović, Budimir S. Ilić, Milka Vrecl, Tomaž Trobec, Kristina Sepčić, Robert Frangež, Sanja Glisic, Jelena S. Milićević
Izvirni znanstveni članek
Oznake: cholinesterases;enzyme inhibition;pesticides;electron-ion interaction potential;molecular docking;molecular dynamics simulations;
ǂThe ǂgrowing demand for agricultural products has led to the misuse of pesticides, resulting in the use of higher concentrations of these substances. This has led to an increase in toxicity imposed on other beneficial organisms and to the bioaccumulation of toxic pesticide concentrations in the bod ...
Leto: 2025 Vir: Veterinarska fakulteta (UL VF)
Št. zadetkov: 4
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