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Št. zadetkov: 3
Lipoprotein(a)-the crossroads of atherosclerosis, atherothrombosis and inflammation
Sabina Ugovšek, Miran Šebeštjen
Pregledni znanstveni članek
Oznake: lipoprotein(a);atherothrombosis;inflammation;coagulation;fibrinolysis;
Increased lipoprotein(a) (Lp(a)) levels are an independent predictor of coronary artery disease (CAD), degenerative aortic stenosis (DAS), and heart failure independent of CAD and DAS. Lp(a) levels are genetically determinated in an autosomal dominant mode, with great intra- and inter-ethnic diversi ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Effect of PCSK9 inhibitors on regulators of lipoprotein homeostasis, inflammation and coagulation
Patricija Lunar, Hana Meglič, Mateja Vehar, Sabina Ugovšek, Andreja Rehberger Likozar, Miran Šebeštjen, Janja Zupan
Izvirni znanstveni članek
Oznake: PCSK9 inhibitors;lipid regulators;inflammation;coagulation;coronary artery disease;
Background: PCSK9 inhibitors (PCSK9i) represent a newer form of atherosclerosis treatment. Inflammation and haemostasis are key processes in the development of atherosclerosis. In this study, we investigated the influence of therapy with PCSK9i in patients with coronary artery disease (CAD) on regul ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Gain of function variants in PCSK9 gene in high risk patients after myocardial infarction with increased lipoprotein (a) values and treated with statins
Sabina Ugovšek, Andreja Rehberger Likozar, Tina Levstek, Katarina Trebušak Podkrajšek, Janja Zupan, Slobodan Antonić, Miran Šebeštjen
Izvirni znanstveni članek
Oznake: polimorfizmi PCSK9;lipoprotein(a);endotelijska disfunkcija;skupne ravni PCSK9;PCSK9 polymorphisms;endothelial dysfunction;total PCSK9 levels;
The proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates lipid metabolism, inflammation and haemostasis. Pathogenic gain-of-function variants in the PCSK9 gene are causative of autosomal-dominant form of familial hypercholesterolemia, while several PCSK9 alleles have been associated with ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 3
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