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High doses of ivermectin cause toxic effects after shortterm oral administration in rats
Vladimir Marjanović, Dragana Medić, Djordje S. Marjanović, Nenad Andrić, Miloš Ž. Petrović, Jelena Francuski Andrić, Milena Radaković, Vanja Krstić, Saša Trailović
Izvirni znanstveni članek
Oznake: ivermectin;toxicity;SARS-CoV-2;cytochrome P-450;P-gp;histopathological changes;rats;
The anthelmintic macrocyclic lactones (MLs) are the most important endec-tocides in modern pharmacotherapy of parasitic infections. However, during the COVID 19 pandemic, ivermectin was used in humans against infection with the SARS-CoV-2 virus in doses significantly higher than the approved antipar ...
Leto: 2024 Vir: Veterinarska fakulteta (UL VF)
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