Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 5
Synthesis of [ [sup] 2H [sub] 5]baricitinib via [ [sup] 2H [sub] 5]ethanesulfonyl chloride
Ross D. Jansen-van Vuuren, Rahul Vohra
Izvirni znanstveni članek
Oznake: baricitinib;COVID-19;devteracija;označevanje z devterijem;SARS-CoV-2;izotopolog;deuteration;deuterium-labelled;isotopologue;
Baricitinib, typically applied as a treatment for rheumatoid arthritis, has recently attracted the attention of clinicians and researchers as a potential treatment for COVID-19. Naturally, there has been a need for the preparation of the isotope-labelled analogue of baricitinib to probe the pharmaco ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Deuterated drugs and biomarkers in the COVID-19 pandemic
Ross D. Jansen-van Vuuren, Luka Jedlovčnik, Janez Košmrlj, Thomas E. Massey, Volker Derdau
Pregledni znanstveni članek
Oznake: COVID-19;izotopi vodika;inhibitorji;presnova;zdravila;hydrogen isotopes;inhibitors;metabolism;pharmaceuticals;
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially identified in Wuhan (China) in December 2019, COVID-19 rapidly spread globally, resulting in the COVID-19 pandemic. Carriers of the SARS-CoV-2 can ...
Leto: 2022 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Towards structurally versatile mesoionic N-heterocyclic olefin ligands and their coordination to palladium, gold, and boron hydride
Tisa Ževart, Balazs Pinter, Matic Lozinšek, Damijana Urankar, Ross D. Jansen-van Vuuren, Janez Košmrlj
Izvirni znanstveni članek
Oznake: coordination;boron hydride;
We have developed an efficient and versatile approach for the synthesis of a family of 1,2,3-triazole-based mesoionic N-heterocyclic olefin (mNHO) ligands and investigated their coordination to palladium, gold, and boron hydride experimentally and computationally. We reacted mNHOs obtained through d ...
Leto: 2024 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
ǂThe ǂversatile and strategic O-carbamate directed metalation group in the synthesis of aromatic molecules
Ross D. Jansen-van Vuuren, Susana Liu, M. A. Jalil Miah, Janez Cerkovnik, Janez Košmrlj, Victor Snieckus
Pregledni znanstveni članek
Oznake: aril O-karbamat;metalizacija;preureditev;navzkrižna sklopitev;regioselektivnost;usmerjevalna skupina;aryl O-carbamate;metalation;rearrangement;cross coupling;regioselective;directing group;
The aryl O-carbamate (ArOAm) group is among the strongest of the directed metalation groups (DMGs) in directed ortho metalation (DoM) chemistry, especially in the form Ar-OCONEt$_2$. Since the last comprehensive review of metalation chemistry involving ArOAms (published more than 30 years ago), the ...
Leto: 2024 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Probing Alzheimer's pathology
Luka Rejc, Damijan Knez, Gabriela Molina-Aguirre, Alba Espargaró, Jerneja Kladnik, Anže Meden, Lana Blinc, Matic Lozinšek, Ross D. Jansen-van Vuuren, Matic Rogan, Bruno Aleksander Martek, Jernej Mlakar, Ana Dremelj, Andrej Petrič, Stanislav Gobec, Mara Bresjanac, Janez Košmrlj
Izvirni znanstveni članek
Oznake: amyloid beta;fluorophore;solvatochromism;synthesis;photophysics;
Fluorescent probes are a powerful tool for imaging amyloid β (Aβ) plaques, the hallmark of Alzheimer’s disease (AD). Herein, we report the synthesis and comprehensive characterization of 21 novel probes as well as their optical properties and binding affinities to Aβ fibrils. One of these dyes, 1Ae, ...
Leto: 2024 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 5
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: