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Št. zadetkov: 2
ǂA ǂmulti-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM)
Heather R. Jackson, Judith Zandstra, Stephanie Menikou, Melissa Shea Hamilton, Andrew J McArdle, Roman Fischer, Adam M Thorne, Marko Pokorn, Mojca Kolnik, Katarina Vincek, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: C-reactive protein;antibiotic overuse;virus-infection;resistance;
Background: Differentiating between self-resolving viral infections and bacterial infections in children who are febrile is a common challenge, causing difficulties in identifying which individuals require antibiotics. Studying the host response to infection can provide useful insights and can lead ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Development of the fish invitrome for animal-free environmental risk assessment of chemicals
Marion Revel, Ksenia J Groh, Jessica Bertoli, Mihai-Ovidiu Degeratu, Melanie Fischer, Stephan Fischer, Jarno Hoekman, Barbara Jozef, Roman Li, Anže Županič
Izvirni znanstveni članek
Oznake: sistemska toksikologija;alternative eksperimentom na živalih;mavrična postrv;ekotoksikologija;new approach methodologies (NAMs);rainbow trout cell lines;toxicity testing;socio-technical approach;co-design with stakeholders;
Given the need to reduce animal testing for environmental risk assessment, we aim to develop a fish invitrome, an alternative fish modular framework capable of predicting chemical toxicity in fish without the use of animals. The central module of the framework is the validated RTgill-W1 cell line as ...
Leto: 2025 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 2
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