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Št. zadetkov: 3
Diagnosis of multisystem inflammatory syndrome in children by a whole-blood transcriptional signature
Heather R. Jackson, Luca Miglietta, Dominic Habgood-Coote, Giselle D’Souza, Priyen Shah, Samuel Nichols, Ortensia Vito, Oliver Powell, Maisey Salina Davidson, Chisato Shimizu, Marko Pokorn
Izvirni znanstveni članek
Oznake: COVID-19;diagnostic signature;host diagnostics;host response;multisystem inflammatory syndrome in children;pediatric infectious diseases;rapid diagnostics;transcriptomics;
Background. To identify a diagnostic blood transcriptomic signature that distinguishes multisystem inflammatory syndrome in children (MIS-C) from Kawasaki disease (KD), bacterial infections, and viral infections. Methods. Children presenting with MIS-C to participating hospitals in the United Kingdo ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Plasma protein biomarkers distinguish multisystem inflammatory syndrome in children from other pediatric infectious and inflammatory diseases
Sophya Yeoh, Diego Estrada-Rivadeneyra, Heather R. Jackson, Ilana Keren, Rachel Galassini, Samantha Cooray, Priyen Shah, Philipp K. A. Agyeman, Romain Basmaci, Enitan D Carrol, Marko Pokorn
Izvirni znanstveni članek
Oznake: multisystem inflammatory syndrome;SARS-CoV-2;Kawasaki;pediatric;biomarkers;
Background: Multisystem inflammatory syndrome in children (MIS-C) is a rare but serious hyperinflammatory complication following infection with severe acute respiratory syndrome coronavirus 2. The mechanisms underpinning the pathophysiology of MIS-C are poorly understood. Moreover, clinically distin ...
Leto: 2024 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Relationship between molecular pathogen detection and clinical disease in febrile children across Europe
Priyen Shah, Marie Voice, Leonides Calvo-Bado, Irene Rivero Calle, Sophie Morris, Ruud Nijman, Claire Broderick, Tisham De, Mojca Kolnik, Katarina Vincek, Marko Pokorn, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: molecular diagnostics;diagnostic;febrile illness;infectious disease;bacterial infection;viral infection;respiratory infection;
Background: The PERFORM study aimed to understand causes of febrile childhood illness by comparing molecular pathogen detection with current clinical practice. Methods: Febrile children and controls were recruited on presentation to hospital in 9 European countries 2016–2020. Each child was assigned ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 3
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