Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 4
Prispevek gastrina in genetske variabilnosti kandidatnih genov celičnega cikla k razvoju raka želodca
Pia Pužar Dominkuš, Petra Hudler
Doktorska disertacija
Oznake: rak želodca;gastrin;polimorfizem posameznega nukleotida (SNP);eksosomi;mikrovezikli;veliki onkosomi;zunajcelični vezikli;PLK2;miR-23b-5p;celični cikel;
V doktorskem delu smo preučevali molekularne in genetske dejavnike, ki prispevajo k nastanku in napredovanju raka želodca. Mednje uvrščamo hipergastrinemijo, ki dolgoročno spodbuja celično proliferacijo ter zavira apoptozo, zunajcelične vezikle, ki med celicami prenašajo onkogene, ter polimorfizme p ...
Leto: 2023 Vir: Medicinska fakulteta (UL MF)
Analysis of miR-9-5p, miR-124-3p, miR-21-5p, miR-138-5p, and miR-1-3p in glioblastoma cell lines and extracellular vesicles
Alja Zottel, Neja Zupanec, Ana Kump, Lucija Raspor Dall'Olio, Pia Pužar Dominkuš, Rok Romih, Samo Hudoklin, Jernej Mlakar, Daniil Nikitin, Maxim Sorokin, Anton A. Buzdin, Ivana Jovchevska, Radovan Komel
Izvirni znanstveni članek
Oznake: glioblastom;biomarkerji;eksosomi;glioblastoma;biomarkers;exosomes;
Glioblastoma (GBM), the most common primary brain tumor, is a complex and extremely aggressive disease. Despite recent advances in molecular biology, there is a lack of biomarkers, which would improve GBM's diagnosis, prognosis, and therapy. Here, we analyzed by qPCR the expression levels of a set o ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
HIV protein Nef expression in human microglia drives the release of distinct Nef-containing extracellular vesicles
Teja Lavrin, Jure Loboda, Jana Ferdin, Valentina Levak, Simona Sitar, Marija Holcar, Pia Pužar Dominkuš, Metka Lenassi, Nataša Resnik, Matjaž Stenovec, Alenka Trampuš-Bakija, Peter Veranič, Ema Žagar, Magda Tušek-Žnidarič
Izvirni znanstveni članek
Oznake: human immunodeficiency virus (HIV);microglia;protein Nef;extracellular vesicles (EVs);HIV-associated neurocognitive disorder (HAND);
Aim: Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) persist in effectively treated HIV-infected individuals, in part due to HIV reservoirs in brain microglia, which express low levels of viral proteins such as Nef. This study aimed to elucidate how microglia release Ne ...
Leto: 2025 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Altered NRF2 signalling in systemic redox imbalance: Insights from non-communicable diseases
Monika Jakubowska, Vera Marisa Costa, Wojciech Krzeptowski, Pia Pužar Dominkuš, Marlene Santos, Birsen Can Demirdöğen, Şermin Genç, Ioannis P. Trougakos, Katja M. Kanninen, Brigitte M. Winklhofer-Roob, Vita Dolžan
Pregledni znanstveni članek
Oznake: biomarker;NRF2;non-communicable diseases;oxidative stress;radox imbalance;transcription factor;
The balanced activity of the cytoprotective transcription factor NRF2 is central for maintaining redox, metabolic-energetics, and proteome homeostasis, as well as for regulating inflammatory responses, among other functions. Activated NRF2 regulates the expression of hundreds of genes containing ant ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 4
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: