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Št. zadetkov: 6
Impact of infection on proteome-wide glycosylation revealed by distinct signatures for bacterial and viral pathogens
Esther Willems, Jolein Gloerich, Anouk Suppers, Michiel Van der Flier, Marko Pokorn, Mojca Kolnik, Katarina Vincek, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: plasma;roles;glycoproteomics;biomarkers;profiles;children;glycome;
Mechanisms of infection and pathogenesis have predominantly been studied based on differential gene or protein expression. Less is known about posttrans-lational modifications, which are essential for protein functional diversity. We applied an innovative glycoproteomics method to study the systemic ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Relationship between molecular pathogen detection and clinical disease in febrile children across Europe
Priyen Shah, Marie Voice, Leonides Calvo-Bado, Irene Rivero Calle, Sophie Morris, Ruud Nijman, Claire Broderick, Tisham De, Mojca Kolnik, Katarina Vincek, Marko Pokorn, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: molecular diagnostics;diagnostic;febrile illness;infectious disease;bacterial infection;viral infection;respiratory infection;
Background: The PERFORM study aimed to understand causes of febrile childhood illness by comparing molecular pathogen detection with current clinical practice. Methods: Febrile children and controls were recruited on presentation to hospital in 9 European countries 2016–2020. Each child was assigned ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Emergency medical services utilisation among febrile children attending emergency departments across Europe
Chantal D. Tan, Clementien L. Vermont, Joany M. Zachariasse, Ulrich Von Both, Irini Eleftheriou, Marieke Emonts, Michiel Van der Flier, Jethro Adam Herberg, Marko Pokorn, Mojca Kolnik, Katarina Vincek, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: emergency medical services;emergency care;children;fever;paediatrics;
Children constitute 6–10% of all patients attending the emergency department (ED) by emergency medical services (EMS). However, discordant EMS use in children occurs in 37–61% with fever as an important risk factor. We aimed to describe EMS utilisation among febrile children attending European EDs. ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care
Laura Kolberg, Aakash Khanijau, Fabian Johannes Stanislaus Van der Velden, Jethro Adam Herberg, Tisham De, Rachel Galassini, Aubrey J. Cunnington, Victoria J. Wright, Marko Pokorn, Mojca Kolnik, Katarina Vincek, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: antimicrobial stewardship;pediatric emergency care;antibiotic prescription;AWaRe;infectious diseases;
Background: Optimization of antimicrobial stewardship is key to tackling antimicrobial resistance, which is exacerbated by overprescription of antibiotics in pediatric emergency departments (EDs). We described patterns of empiric antibiotic use in European EDs and characterized appropriateness and c ...
Leto: 2024 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Febrile illness in high-risk children
Fabian Johannes Stanislaus Van der Velden, Gabriella De Vries, Alexander James Martin, Emma Lim, Ulrich Von Both, Laura Kolberg, Enitan D Carrol, Aakash Khanijau, Marko Pokorn, Mojca Kolnik, Katarina Vincek, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: immunocompromised;paediatric;children;fever;infection;antibiotics;
To assess and describe the aetiology and management of febrile illness in children with primary or acquired immunodeficiency at high risk of serious bacterial infection, as seen in emergency departments in tertiary hospitals. Prospective data on demographics, presenting features, investigations, mic ...
Leto: 2023 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Guideline adherence in febrile children below 3 months visiting European Emergency Departments
Chantal D. Tan, Eline E. P. L. van der Walle, Clementien L. Vermont, Ulrich Von Both, Enitan D Carrol, Irini Eleftheriou, Marieke Emonts, Michiel Van der Flier, Ronald De Groot, Marko Pokorn, Mojca Kolnik, Katarina Vincek, Tina Plankar Srovin, Natalija Bahovec, Petra Prunk, Veronika Osterman, Tanja Avramoska
Izvirni znanstveni članek
Oznake: fever;children;pediatrics;guideline;emergency care;
Febrile children below 3 months have a higher risk of serious bacterial infections, which often leads to extensive diagnostics and treatment. There is practice variation in management due to differences in guidelines and their usage and adherence. We aimed to assess whether management in febrile chi ...
Leto: 2022 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 6
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