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Št. zadetkov: 2
Identification of novel RNA binding proteins influencing circular RNA expression in hepatocellular carcinoma
Rok Razpotnik, Petra Nassib, Tanja Kunej, Damjana Rozman, Tadeja Režen, Tadeja Režen
Izvirni znanstveni članek
Oznake: hepatocelularni karcinom;krožna RNA;identifikacija novih proteinov;hepatocellular carcinoma;circular RNA;identification of novel proteins;
Circular RNAs (circRNAs) are increasingly recognized as having a role in cancer development. Their expression is modified in numerous cancers, including hepatocellular carcinoma (HCC); however, little is known about the mechanisms of their regulation. The aim of this study was to identify regulators ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Knockouts of CYP51A1, DHCR24, or SC5D from cholesterol synthesis reveal pathways modulated by sterol intermediates
Cene Skubic, Hana Trček, Petra Nassib, Tinkara Kreft, Andrew Walakira, Katka Pohar, Sara Petek, Tadeja Režen, Alojz Ihan, Damjana Rozman, Damjana Rozman
Izvirni znanstveni članek
Oznake: cholesterol synthesis;sterol intermediates;CYP51A1;DHCR24;SC5D;
Sterols from cholesterol synthesis are crucial for cholesterol production, but also have individual roles difficult to assess in vivo due to essentiality of cholesterol. We developed HepG2 cell models with knockouts (KOs) for three enzymes of cholesterol synthesis, each accumulating specific sterols ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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