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Št. zadetkov: 2
Catalytic stereoconvergent synthesis of homochiral [beta]-CF[sub]3, [beta]-SCF[sub]3, and [beta]-OCF[sub]3 benzylic alcohols
Andrej Emanuel Cotman, Pavel A. Dub, Maša Sterle, Matic Lozinšek, Jaka Dernovšek, Živa Zajec, Anamarija Zega, Tihomir Tomašić, Dominique Cahard
Izvirni znanstveni članek
Oznake: adaptive crystals;asymmetric catalysis;density functional calculations;drug design;fluorine;hydrogenation;kinetic resolution;ruthenium;alcohols;catalysts;crystals;ketones;stereoselectivity;
We describe an efficient catalytic strategy for enantio- and diastereoselective synthesis of homochiral β-CF$_3$, β-SCF$_3$, and β-OCF$_3$ benzylic alcohols. The approach is based on dynamic kinetic resolution (DKR) with Noyori−Ikariya asymmetric transfer hydrogenation leading to simultaneous constr ...
Leto: 2022 Vir: Fakulteta za farmacijo (UL FFA)
Predicting the spatio-temporal risk of human tick-borne encephalitis (TBE) in Europe by combining hazard and exposure drivers
Francesca Dagostin, Francesca Dagostin, Diana Erazo, Giovanni Marini, Daniele Da Re, Valentina Tagliapietra, Maria Avdicova, Tatjana Avšič-Županc, Timothée Dub, Nahuel Fiorito, Nataša Knap
Izvirni znanstveni članek
Oznake: boosted regression trees;ecological niche modelling;Europe;tick-borne encephalitis;one health;vector-borne disease;
Background: Tick-borne encephalitis (TBE), caused by tick-borne encephalitis virus (TBEV), is a zoonotic disease that can lead to severe neurological symptoms. Given the increasing number of reported human TBE cases in Europe, we developed a spatio-temporal predictive model to infer the year-to-year ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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