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Differential effects of young and old hematopoietic stem cell niches on bone marrow-derived dendritic cells
Patrik Milić, Mojca Justin, Katerina Jazbec, Urban Švajger, Primož Rožman
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Oznake: hematopoietic stem cells;HSC niche;inflammation;aging;dendritic cells;bone marrow-derived dendritic cells;BM adipocytes;
Background: Aging is linked to various dysfunctions of the immune system, including the decline of its primary developmental source: the hematopoietic stem cell (HSC) niche. This decline leads to chronic inflammation, increased vulnerability to infections, cancer, autoimmune diseases, and reduced va ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
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