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Št. zadetkov: 2
Proprotein convertase subtilisin/kexin type 9–CC-motif chemokine ligand 2 interactions link lipoprotein(a) composition to intermediate monocyte inflammation in coronary artery disease
Sabina Ugovšek, Andreja Rehberger Likozar, Tina Levstek, Katarina Trebušak Podkrajšek, Janja Zupan, Frieda Marka, Tamara Trimmel, Mira Brekalo, Walter Speidl, Philipp Hohensinner, Patrick Haider, Miran Šebeštjen
Izvirni znanstveni članek
Oznake: PCSK9;Lp(a);monocytes (monociti);
Background: Intermediate monocytes (IM) exhibit proinflammatory properties and contribute to atherosclerosis. Elevated lipoprotein(a) [Lp(a)] levels modulate monocyte behavior, while proprotein convertase subtilisin/kexin type 9 (PCSK9) has been implicated in inflammatory pathways beyond lipid metab ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
PCSK9 inhibitors increase CD34+ but not other endothelial progenitor cells in patients with chronic coronary disease and increased Lp(a) values
Sabina Ugovšek, Andreja Rehberger Likozar, Tina Levstek, Katarina Trebušak Podkrajšek, Janja Zupan, Frieda Marka, Tamara Trimmel, Mira Brekalo, Walter Speidl, Philipp Hohensinner, Patrick Haider, Miran Šebeštjen
Izvirni znanstveni članek
Oznake: endothelial function;endothelial progenitor cells;CD34+;lipoprotein(a);proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors (PCSK9i);myocardial infarction;
Background: Endothelial dysfunction is an independent predictor of cardiovascular events in patients with established atherosclerosis, while the circulating levels of endothelial progenitor cells (EPCs) reflect active endothelial function in heart failure patients. Although protein convertase subtil ...
Leto: 2026 Vir: Repozitorij Univerze v Ljubljani (RUL)
Št. zadetkov: 2
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