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Št. zadetkov: 3
Strategies to overcome hematocrit and volume bias in dried blood spot analysis
Panagiotis-Dimitrios Mingas, Panagiotis-Dimitrios Mingas, Matjaž Cirar, Iztok Grabnar, David Drobne, Tomaž Vovk, Tomaž Vovk
Izvirni znanstveni članek
Oznake: dried blood spots;DBS;microsampling;blood volume;hematocrit;image analysis;conductivity;spectrometry;bias;
Background/Objectives: Dried blood spot (DBS) sampling, a technique for collecting capillary blood samples, is widely used in therapeutic drug monitoring, pharmacokinetic and toxicology research, newborn screening, and population health because it enables simple, non-invasive sampling across large c ...
Leto: 2026 Vir: Fakulteta za farmacijo (UL FFA)
ǂThe ǂevolving role of microsampling in therapeutic drug monitoring of monoclonal antibodies in inflammatory diseases
Panagiotis-Dimitrios Mingas, Jurij Zdovc, Iztok Grabnar, Tomaž Vovk
Pregledni znanstveni članek
Oznake: microsampling;DBS;VAMS;mAbs;TDM;inflammatory diseases;
Monoclonal antibodies (mAbs) have been extensively developed over the past few years, for the treatment of various inflammatory diseases. They are large molecules characterized by complex pharmacokinetic and pharmacodynamic properties. Therapeutic drug monitoring (TDM) is routinely implemented in th ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Development, validation and application of the dried blood spot analysis method for the determination of Ustekinumab in patients with Inflammatory bowel disease
Panagiotis-Dimitrios Mingas, Jurij Zdovc, Iztok Grabnar, David Drobne, Tomaž Vovk
Izvirni znanstveni članek
Oznake: ustekinumab;dried blood spots;venous blood;capillary blood;validation;inflammatory bowel disease;ELISA;
Background: Ustekinumab (UST) is a monoclonal antibody (mAb) used in the treatment of inflammatory bowel disease (IBD). Elevated serum concentrations are typically associated with improved therapeutic outcomes, and therapeutic drug monitoring (TDM) is a useful tool for guiding mAbs treatment. This s ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 3
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