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Effect of diflunisal and purine synthesis inhibitors on AMP-activated protein kinase and insulin action in skeletal muscle cells
Klemen Dolinar, Sergej Pirkmajer, Pablo Miguel Garcia-Roves
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Oznake: AMP-activated protein kinase (AMPK);diflunisal;inhibitors of de novo purine synthesis;inhibitors of folate metabolism;insulin;skeletal muscle cells;
BACKGROUND: Skeletal muscles are an important site of glucose uptake and utilization and therefore play an important role in whole-body glucose homeostasis, making them an important target for the treatment of diabetes. One promising approach for the treatment of diabetes is activation of AMP-activa ...
Leto: 2025 Vir: Medicinska fakulteta (UL MF)
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