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Št. zadetkov: 2
From biomarker discovery to clinical applications of metabolomics in glioblastoma
Neja Šamec, Gloria Krapež, Cene Skubic, Ivana Jovchevska, Alja Videtič Paska
Pregledni znanstveni članek
Oznake: Omics;metabolome;multiomic integration;tumor metabolic reprogramming;biomarker;diagnosis;therapy;precision oncology;
Background/Objectives: In recent years, interest in studying changes in cancer metabolites has resulted in significant advances in the metabolomics field. Glioblastoma remains the most aggressive and lethal brain malignancy, which presents with notable metabolic reprogramming. Methods: We performed ...
Leto: 2025 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
In vitro functional validation of an anti-FREM2 nanobody for glioblastoma cell targeting
Gloria Krapež, Neja Šamec, Alja Zottel, Mojca Katrašnik, Ana Kump, Jernej Šribar, Ivana Jovchevska, Igor Križaj, Jure Stojan, Rok Romih, Gregor Bajc, Matej Butala, Serge Muyldermans
Izvirni znanstveni članek
Oznake: brain cancer;membrane-bound protein;cytotoxicity;molecular tool;subcellular localization;
Background/Objectives: Glioblastomas are the most common brain malignancies. Despite the implementation of multimodal therapy, patient life expectancy after diagnosis is barely 12 to 18 months. Glioblastomas are highly heterogeneous at the genetic and epigenetic level and comprise multiple different ...
Leto: 2025 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 2
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