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ǂA ǂnovel butyrylcholinesterase inhibitor induces antidepressant, pro-cognitive, and anti-anhedonic effects in Flinders Sensitive Line rats
Nadia Olivier, Brian H. Harvey, Stanislav Gobec, Shahid Mohammed, Urban Košak, Simon Žakelj, Christiaan B. Brink
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Oznake: depression;butyrylcholinesterase inhibitor;GhrelinD;Lys-3-GHRP-6;dopamine;cognition;anhedonia;reward;
Background and purpose: Major depressive disorder (MDD) is often treatment resistant, particularly in addressing anhedonia and cognitive deficits. Novel pharmacological strategies are needed. While butyrylcholinesterase, ghrelin, and dopamine (DA) have been well studied in the context of stress and ...
Leto: 2025 Vir: Fakulteta za farmacijo (UL FFA)
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