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Št. zadetkov: 2
ǂThe ǂincidence of IgG4-related disease in Slovenia
Alojzija Hočevar, Aleš Grošelj, Gregor Hawlina, Matic Koželj, Andrej Škoberne, Jože Pižem, Vesna Jurčić
Izvirni znanstveni članek
Oznake: IgG4-related disease;epidemiology;demographic;incidence rate;
Background: Data on the incidence of IgG4-related disease (IgG4-RD) are scarce. Our aim was to determine the incidence of IgG4-RD in a well-defined region. Methods: This retrospective study covered the Ljubljana region over the period from January 2012 to December 2024. A review of cases diagnosed w ...
Leto: 2025 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Ustekinumab dosing individualization in Crohn's disease guided by a population pharmacokinetic-pharmacodynamic model
Jurij Zdovc, Jurij Hanžel, Tina Kurent, Nejc Sever, Matic Koželj, Nataša Smrekar, Gregor Novak, Borut Štabuc, Tomaž Vovk, Barbara Ostanek, David Drobne, Iztok Grabnar
Izvirni znanstveni članek
Oznake: vnetje črevesja;terapevtsko spremljanje zdravil;fekalni kalprotektin;ustekinumab;inflammatory bowel disease;fecal calprotectin;pharmacokinetics-pharmacodynamics;therapeutic drug monitoring;
Ustekinumab is a monoclonal antibody used in Crohn's disease (CD). Dose optimization in case of non-response and the role of pharmacokinetic-pharmacodynamic (PK-PD) monitoring remain unresolved dilemmas in clinical practice. We aimed to develop a population PK-PD model for ustekinumab in CD and simu ...
Leto: 2021 Vir: Fakulteta za farmacijo (UL FFA)
Št. zadetkov: 2
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