Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 5
All-atom simulations reveal the effect of membrane composition on the signaling of the NKG2A/CD94/HLA-E immune receptor complex
Martin Ljubič, Andrej Perdih, Jure Borišek
Izvirni znanstveni članek
Oznake: biokemija;proteini;beljakovine;membrane;molekulska dinamika;
Understanding how membrane composition influences the dynamics and function of transmembrane proteins is crucial for the comprehensive elucidation of cellular signaling mechanisms and the development of targeted therapeutics. In this study, we employed all-atom molecular dynamics simulations to inve ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
All-atom simulations reveal the intricacies of signal transduction upon binding of the HLA-E ligand to the transmembrane inhibitory CD94/NKG2A receptor
Martin Ljubič, Eva Prašnikar, Andrej Perdih, Jure Borišek
Izvirni znanstveni članek
Oznake: biokemija;imuski odziv;virusi;bakterije;simulacije;receptorji;
Natural killer (NK) cells play an important role in the innate immune response against tumors and various pathogens such as viruses and bacteria. Their function is controlled by a wide array of activating and inhibitory receptors, which are expressed on their cell surface. Among them is a dimeric NK ...
Leto: 2023 Vir: Fakulteta za farmacijo (UL FFA)
Machine learning heralding a new development phase in molecular dynamics simulations
Eva Prašnikar, Martin Ljubič, Andrej Perdih, Jure Borišek
Pregledni znanstveni članek
Oznake: fizikalna kemija;molekularna dinamika;strojno učenje;simulacije;
Molecular dynamics (MD) simulations are a key computational chemistry technique that provide dynamic insight into the underlying atomic-level processes in the system under study. These insights not only improve our understanding of the molecular world, but also aid in the design of experiments and t ...
Leto: 2024 Vir: Fakulteta za farmacijo (UL FFA)
Študij mehanizma toplotne in kemične denaturacije modelnih proteinov s pomočjo FTIR spektroskopije
Martin Ljubič, Jože Grdadolnik, Jurij Lah, Mitja Kolar, San Hadži
Magistrsko delo
Oznake: proteini;hemoglobin;konalbumin;inzulin;denaturacija;agregacija;FTIR spektroskopija;oslabljena popolna refleksija;ATR;magistrska dela;
Infrardeča spektroskopija sodi med manj pogoste metode za preučevanje konformacijskih sprememb proteinov. Kljub temu metoda nudi nekatere prednosti, kot so meritve majhnih količin vzorcev v različnih agregatnih stanjih. Pridobimo lahko informacije o medmolekulskih interakcijah, še posebej pa je meto ...
Leto: 2021 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Computational study of the HLTF ATPase remodeling domain suggests its activity on dsDNA and implications in damage tolerance
Martin Ljubič, Claudia D'Ercole, Yossma Waheed, Ario De Marco, Jure Borišek, Matteo De March
Izvirni znanstveni članek
Oznake: DNA repairing mechanism;protein modeling;chromatin remodeler;helicase-like transcription factor;
Computational study of the HLTF ATPase remodeling domain suggests its activity on dsDNA and implications in damage tolerance
Leto: 2024 Vir: Repozitorij Univerze v Novi Gorici (RUNG)
Št. zadetkov: 5
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: