Št. zadetkov: 12
Izvirni znanstveni članek
Oznake:
podjetja;poslovni ugled;družbena odgvornost;zaupanje;
Leto:
2011
Vir:
dLib.si Digitalna knjižnica Slovenije
Izvirni znanstveni članek
Oznake:
baricitinib;COVID-19;devteracija;označevanje z devterijem;SARS-CoV-2;izotopolog;deuteration;deuterium-labelled;isotopologue;
Baricitinib, typically applied as a treatment for rheumatoid arthritis, has recently attracted the attention of clinicians and researchers as a potential treatment for COVID-19. Naturally, there has been a need for the preparation of the isotope-labelled analogue of baricitinib to probe the pharmaco ...
Leto:
2022
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Pregledni znanstveni članek
Oznake:
imobiliziran;primeren za recikliranje;katalizator;deuteriranje;kemija s kontinuiranim pretokom;izotopska izmenjava;označevanje z devterijem;nosilec;immobilized;suitable for recycling;catalyst;deuteration;continuous-flow chemistry;isotope exchange;deuterium labeling;carrier;
Deuterated compounds have become indispensable across a wide range of applications in medicinal chemistry and materials science, driving interest in the development of efficient and sustainable synthetic methodologies. In particular, there is a growing emphasis on greener approaches that enable deut ...
Leto:
2026
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Pregledni znanstveni članek
Oznake:
COVID-19;izotopi vodika;inhibitorji;presnova;zdravila;hydrogen isotopes;inhibitors;metabolism;pharmaceuticals;
Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Initially identified in Wuhan (China) in December 2019, COVID-19 rapidly spread globally, resulting in the COVID-19 pandemic. Carriers of the SARS-CoV-2 can ...
Leto:
2022
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Izvirni znanstveni članek
Oznake:
coordination;boron hydride;
We have developed an efficient and versatile approach for the synthesis of a family of 1,2,3-triazole-based mesoionic N-heterocyclic olefin (mNHO) ligands and investigated their coordination to palladium, gold, and boron hydride experimentally and computationally. We reacted mNHOs obtained through d ...
Leto:
2024
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Izvirni znanstveni članek
Oznake:
devteriranje;usmerjeno orto-metaliranje;orto-devteriranje;N-heterocikli;O-karbamati;karboksamidi;deuteration;directed ortho-matalation;ortho-deuteration;N-heterocycles;O-carbamates;carboxamides;
Selectively deuterated electron-deficient N-containing heteroaromatic systems can enable modulation of metabolism with enhanced therapeutic efficacy in pharmaceuticals and improved properties and stability of functional materials, e.g., imaging dyes, light emitters, and catalysts. Current synthetic ...
Leto:
2025
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Pregledni znanstveni članek
Oznake:
deuteriranje;devterij;označevanje z devterijem;označevanje z izotopi;N-heteroaren;N-heteroaromatski;piridin;pirimidin;pirazin;piridazin;kinolin;kinazolin;elektronsko pomanjkljiv;triazin;tetrazin;organska elektronika;farmacevtski izdelki;barvila;deuteration;deuterium;deuterium-labelling;isotope-labelling;N-heteroarene;N-heteroaromatic;pyridine;pyrimidine;pyrazine;pyridazine;quinoline;quinazoline;electron-deficient;triazine;tetrazine;organic electronics;pharmaceuticals;dyes;
Six-membered N-heteroarenes (“6NHetAr”) play pivotal roles in the pharmaceutical, agrochemical, and materials science industries. In recent times, deuterium (D)-labelled 6NHetAr have demonstrated enhanced performance over their unlabelled counterparts. For example, VV116 and VX-984, approved therape ...
Leto:
2025
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Pregledni znanstveni članek
Oznake:
aril O-karbamat;metalizacija;preureditev;navzkrižna sklopitev;regioselektivnost;usmerjevalna skupina;aryl O-carbamate;metalation;rearrangement;cross coupling;regioselective;directing group;
The aryl O-carbamate (ArOAm) group is among the strongest of the directed metalation groups (DMGs) in directed ortho metalation (DoM) chemistry, especially in the form Ar-OCONEt$_2$. Since the last comprehensive review of metalation chemistry involving ArOAms (published more than 30 years ago), the ...
Leto:
2024
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Pregledni znanstveni članek
Oznake:
imobiliziran;recikliranje;deuteriran;deuterogenacija;deuteracija;deuterodehalogenacija;deuterodekarboksilacija;immobilized;recyclable;deuterated;deuterogenation;deuteration;deuterodehalogenation;deuterodecarboxylation;
Deuterium(D)-labelled organic compounds are used in many applications e.g., as therapeutic agents, internal standards in drug discovery and development, and new functional materials including dyes, catalysts, and light emitters. Conventionally, the synthesis of D-labelled compounds relies on (bio)ca ...
Leto:
2025
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Yuting Li,
C. Grazia Bezzu,
Anže Zupanc,
Luis Simbari,
Shrestha Banerjee,
Dominik J. Kubicki,
Tomislav Friščić,
Marjan Jereb,
Ross D. Jansen-van Vuuren,
Mariolino Carta,
Stefan Bräse
Izvirni znanstveni članek
Oznake:
poliimid;[2.2]paraciklofan;ločevanje plinov;polimeri z lastno mikroporoznostjo;mikroporozni polimeri;polyimide;[2.2]paracyclophane;gas separation;polymers of intrinsic microporosity;microporous polymers;
Polyimides (PIs) are a significant class of high-performance polymers due to their exceptional thermal, mechanical, and chemical stability. Their combination with polymers of intrinsic microporosity (PIMs) provides access to materials with structural robustness coupled with permanent microporosity. ...
Leto:
2026
Vir:
Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)