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Depression is a common and heterogeneous mental disorder. When a patient, diagnosed with depression, does not achieve an adequate response to treatment with at least two antidepressants, it is considered that patient has developed a treatment-resistant depression (TRD). As an alternative treatment f ...

Depression and anxiety are common mental disorders that often occur together. Stress is an important risk factor for both disorders, affecting pathophysiological processes through epigenetic changes that mediate gene–environment interactions. In this study, we explored two proposed models about the ...

Background. Neuron specific enolase (NSE) is an isomer of the glycolytic enzyme enolase, which was first found in extracts of brain tissue, and was later shown to be present in neuroendocrine cells and neuroendocrine tumours. The aim of the study was to confirm the importance of serum NSE as a tumou ...