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Št. zadetkov: 2
Designing the DNA-intercalating moiety to improve the safety and efficacy of novel bacterial topoisomerase inhibitors
Maša Zorman, Živa Zajec, Irena Zdovc, L. Šenerović, Natasa Radakovic, Marija Atanasković, Marko Anderluh, Nikola Minovski, Martina Hrast
Izvirni znanstveni članek
Oznake: bacteria;peptides and proteins;extraction;inhibition;nuclear magnetic resonance spectroscopy;
Novel bacterial topoisomerase inhibitors (NBTIs) target bacterial topoisomerases through binding modes distinct from fluoroquinolones but are often limited by hERG channel inhibition. Our previous findings indicated that the introduction of a non-aminopiperidine linker and a halogenated phenyl enzym ...
Leto: 2026 Vir: Fakulteta za farmacijo (UL FFA)
ǂThe ǂnew occurrence of antiphospholipid syndrome in severe COVID-19 cases with pneumonia and vascular thrombosis could explain the post-COVID syndrome
Mirjana Zlatković Švenda, Melanija Rašić, Milica Ovuka, Slavica Pavlov Dolijanović, Marija Atanasković Popović, Manca Ogrič, Polona Žigon, Snežna Sodin-Šemrl, Marija Zdravković, Goran Radunović
Izvirni znanstveni članek
Oznake: COVID-19;SARS-CoV2;anti-phosphatidylserine-prothrombin (aPS/PT) antibodies;anti-β2-glycoprotein I (anti-β2GPI) antibodies;anticardiolipin (aCL) antibodies;antiphospholipid antibodies (aPLs);antiphospholipid syndrome;immunology;post-COVID syndrome;vascular thrombosis;
Introduction: The classification of antiphospholipid syndrome (APS) comprises clinical criteria (vascular thrombosis or obstetric complications throughout life) and laboratory criteria (antiphospholipid antibodies (aPLs) positivity, confirmed at least twice at 12-week interval). Methods: In 100 pati ...
Leto: 2025 Vir: Repozitorij Univerze v Ljubljani (RUL)
Št. zadetkov: 2
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