Iskalni niz:
išči po
išči po
išči po
išči po
Vrsta gradiva:
Jezik:
Št. zadetkov: 2
Algorithmically deduced FREM2 molecular pathway is a potent grade and survival biomarker of human gliomas
Marianna Zolotovskaia, Victor Tkachev, Maxim Sorokin, Andrew Garazha, Ella Kim, Sven Rainer Kantelhardt, Alja Zottel, Neja Zupanec, Ivana Jovchevska
Izvirni znanstveni članek
Oznake: gliom;glioblastom;napoved preživetja;glioma;glioblastoma;survival prognosis;
Gliomas are the most common malignant brain tumors with high mortality rates. Recently we showed that the FREM2 gene has a role in glioblastoma progression. Here we reconstructed the FREM2 molecular pathway using the human interactome model. We assessed the biomarker capacity of FREM2 expression and ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Bioinformatic and clinical experimental assay uncovers resistance and susceptibility mechanisms of human glioblastomas to temozolomide and identifies new combined and individual survival biomarkers outperforming MGMT promoter methylation
Alexander Modestov, Marianna Zolotovskaia, Maria Suntsova, Galina Zakharova, Aleksander Seryakov, Ivana Jovchevska, Jernej Mlakar, Elena Poddubskaya, Aleksey Moisseev, Grigory Vykhodtsev
Izvirni znanstveni članek
Oznake: DNA repair pathways;MGMT;Oncobox drug score;WHO CNS5;gene expression biomarker;glioblastoma;
Background: Glioblastoma (GBM) is the most aggressive and lethal central nervous system (CNS) tumor. The treatment strategy is mainly surgery and/or radiation therapy, both combined with adjuvant temozolomide (TMZ) chemotherapy. Historically, methylation of MGMT gene promoter is used as the major bi ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
Ključne besede:
Leto izdaje:
Avtorji:
Repozitorij:
Tipologija:
Jezik: