Št. zadetkov: 35
Pregledni znanstveni članek
Oznake:
ledvice;delovanje;kardiorenalna funkcija;presnovne spremembe;mikrogravitacija;cardiorenal function;metabolic changes;microgravity;oxidative stress;reproduction;space exposome.;a;
Changes in endocrine and kidney functions have been associated with spaceflight. Here, we discuss the most relevant evidence about the impact of spaceflight on the cardiometabolic system, the cardiorenal function and the reproductive/gonadal axis. Notably, these changes appear to be interrelated wit ...
Leto:
2025
Vir:
Digitalni repozitorij raziskovalnih organizacij Slovenije
Izvirni znanstveni članek
Oznake:
telesna oblika;kost;maščobna masa;mišična masa;presejanje;body shape;bone;fat mass;muscle mass;screening;
Background: Population-specific reference values are needed to accurately contextualise age-related changes in body composition. This study aimed to a) establish age- and sex-specific reference values and cut-points for a range of dual-energy x-ray absorptiometry (DXA) derived metrics of lean mass ( ...
Leto:
2025
Vir:
Repozitorij Univerze na Primorskem (RUP)
Pregledni znanstveni članek
Oznake:
psiho-imunsko-nevro-endokrina mreža;vesoljski izpostavljenostni profil;presnovki, ki izvirajo iz črevesne makrobiote;imunska disregulacija;stresni odzivni mehanizmi;psycho-immune-neuro-endocrine network;spacelift exposome;gut macrobiota-derived metabolites;immune dysregulation;
Spaceflight missions represent a new exposome, unpredicted by evolution. Life-threatening agents activate non-specific stress responses involving the psycho-immune-neuroendocrine network. Themainmolecularpathwaysregulatingthis network and those affectedbyspaceflight exposome/microgravityarereportedi ...
Leto:
2025
Vir:
Repozitorij Univerze na Primorskem (RUP)
Izvirni znanstveni članek
Oznake:
biomarkerji;nevrotični faktor, izhajajoč iz možganov (BDNF);starejši ljudje;presejanje;zdravje skeletnih mišic;biomarkers;brain derived neurotrophic factor (BDNF);older people;sarcopenia;screening;skeletal muscle health;
Background: The scalability of a blood-based sarcopenia assessment has generated interest in circulating markers that may enhance management strategies. Data regarding the relevance of brain derived neurotrophic factor (BDNF), a regulator of neuroplasticity, to sarcopenia in community-dwelling adult ...
Leto:
2025
Vir:
Repozitorij Univerze na Primorskem (RUP)
Izvirni znanstveni članek
Oznake:
Tensiomyography;fiber type;myosin heavy chain;mechanomyography;
Noninvasive estimation of myosin heavy chain composition in human skeletal muscle
Leto:
2011
Vir:
Univerza na Primorskem (UP)
Izvirni znanstveni članek
Oznake:
skeletne mišice;mikrogravitacija;atrofija mišic;avtofagija;skeletal muscles;microgravity;muscle atrophy;autophagy;
Skeletal muscle undergoes atrophy and loss of force during long space missions, when astronauts are persistently exposed to altered gravity and increased ionizing radiation. We previously carried out mass spectrometry-based proteomics from skeletal muscle biopsies of two astronauts, taken before and ...
Leto:
2024
Vir:
Univerza na Primorskem (UP)
Izvirni znanstveni članek
Oznake:
otrok;debelost;ultrazvok;child;obesity;ultrasound;
ntroduction Ultrasonography is a non-invasive and safe method for assessing muscle morphology. Among its parameters, echo intensity (EI), derived from grayscale image analysis, has emerged as a promising indicator of muscle quality and intramuscular fat infiltration. This study aims to validate EI a ...
Leto:
2025
Vir:
Repozitorij Univerze na Primorskem (RUP)
Kratki znanstveni prispevek
Oznake:
muscles;cancer cachexia;exercise;metabolic disorders;neuromuscular disorders;resistance training;
Synergist ablation (SA) is a well-established model of mechanical overload-induced hypertrophy in rodents, commonly used toinfer skeletal muscle adaptation to resistance training in humans. Given the critical role of skeletal muscle atrophy in chronicconditions such as neuromuscular, metabolic, and ...
Leto:
2025
Vir:
Repozitorij Univerze na Primorskem (RUP)
Pregledni znanstveni članek
Oznake:
telesna neaktivnost;inzulinska občutljivost;physical inactivity;cage reduction;insulin sensitivity;muscle atrophy;
Physical inactivity represents a heavy burden for modern societies and is spreading worldwide, it is a recognised pandemic and is the fourth cause of global mortality. Not surprisingly, there is an increasing interest in longitudinal studies on the impact of reduced physical activity on different ph ...
Leto:
2023
Vir:
Univerza na Primorskem (UP)
Izvirni znanstveni članek
Oznake:
Ca2+ dynamics;muscle atrophy;neuromuscular junction instability;sarcoplasmic reticulum;single fibre atrophy;single fibre contractile impairment;unloading;
Unloading induces rapid skeletal muscle atrophy and functional decline. Importantly, force is lost at a much higher rate than muscle mass. We aimed to investigate the early determinants of the disproportionate loss of force compared to that of muscle mass in response to unloading. Ten young particip ...
Leto:
2021
Vir:
Repozitorij Univerze na Primorskem (RUP)