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Št. zadetkov: 2
Epigenetics of Alzheimer's disease
Matea Nikolac Perkovic, Alja Videtič, Marcela Konjevod, Katarina Kouter, Dubravka Svob Strac, Gordana Nedic Erjavec, Nela Pivac
Pregledni znanstveni članek
Oznake: Alzheimerjeva bolezen;epigenetika;metilacija DNA;Alzheimer's disease;epigenetics;DNA methylation;
There are currently no validated biomarkers which can be used to accurately diagnose Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies. Moreover, to date, only symptomatic treatments exist for this progressive neurodegenerative disorder. In the search for new ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Metabolomic Profiling of Extracellular Vesicles Reveals Distinct Metabolic Dysregulation and Treatment-Specific Signatures in Depression
Nikola Balic, Gordana Nedic Erjavec, Marcela Konjevod, Jorge Saiz, Tina Curkovic, Lucija Tudor, Dubravka Svob Strac, Alja Videtič, Julija Šmon, Magda Tušek-Žnidarič
Izvirni znanstveni članek
Oznake: MDD;TRD;metabolomics;extracellular vesicles;duloxetine;bright-light therapy;esketamine;treatment;
Major depressive disorder (MDD) is associated with complex metabolic alterations. In this study, we applied a multiplatform metabolomics approach (GC-MS and LC-MS) to characterize the plasma extracellular vesicle (EV) metabolome in healthy controls (N = 50), responsive MDD patients (N = 60), and pat ...
Leto: 2026 Vir: Medicinska fakulteta (UL MF)
Št. zadetkov: 2
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