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Št. zadetkov: 4
Association of genetic polymorphisms in oxidative stress and inflammation pathways with glaucoma risk and phenotype
Makedonka Atanasovska-Velkovska, Katja Goričar, Tanja Blagus, Vita Dolžan, Barbara Cvenkel
Izvirni znanstveni članek
Oznake: glaucoma;inflammation;oxidative stress;
Oxidative stress and neuroinflammation are involved in the pathogenesis and progression of glaucoma. Our aim was to evaluate the impact of selected single-nucleotide polymorphisms in inflammation and oxidative stress genes on the risk of glaucoma, the patients' clinical characteristics and the glauc ...
Leto: 2021 Vir: Medicinska fakulteta (UL MF)
Association of matrix metalloproteinases polymorphisms with glaucoma risk, glaucoma phenotype, and response to treatment with selective laser trabeculoplasty or latanoprost
Makedonka Atanasovska-Velkovska, Katja Goričar, Tanja Blagus, Vita Dolžan, Barbara Cvenkel, Barbara Cvenkel
Izvirni znanstveni članek
Oznake: glaucoma;latanoprost;matrix metalloproteinases;selective laser trabeculoplasty;single nucleotide polymorphisms;
In open-angle glaucoma, the increase in intraocular pressure (IOP) is caused by an increased resistance to aqueous humour outflow in the trabecular meshwork. Since genetic variability of matrix metalloproteinase (MMP) genes may influence extracellular matrix remodelling, we investigated their associ ...
Leto: 2024 Vir: Medicinska fakulteta (UL MF)
Farmakogenetski označevalci odgovora na zdravljenje z latanoprostom ali s selektivno lasersko trabekuloplastiko pri bolnikih s primarnim glavkomom odprtega zakotja in očesno hipertenzijo
Makedonka Atanasovska-Velkovska, Barbara Cvenkel, Vita Dolžan, Danijel Petrovič, Branka Stirn-Kranjc, Tomaž Gračner
Doktorska disertacija
Oznake: Očesne bolezni;Disertacije;Oftalmologija;Glavkom;Zdravljenje;
Uvod: Problem slepote kot posledice glavkoma se povečuje zaradi staranja prebivalstva. Nastanek in napredovanje primarnega glavkoma z odprtim zakotjem (POAG) sta povezana z oksidativnim stresom, vnetjem in apoptozo ganglijskih celic mrežnice. Različni dejavniki lahko povzročijo večje nastajanje reak ...
Leto: 2022 Vir: Medicinska fakulteta (UL MF)
Retinal ganglion cell function and perfusion following intraocular pressure reduction with preservative-free latanoprost in patients with glaucoma and ocular hypertension
Qëndresë Daka, Maja Šuštar, Andrej Meglič, Darko Perovšek, Makedonka Atanasovska-Velkovska, Barbara Cvenkel, Barbara Cvenkel
Izvirni znanstveni članek
Oznake: electroretinogram;optical coherence tomography;optical coherence tomography angiography;preservative-free latanoprost;retinal ganglion cell;
(1) Background: Given the global prevalence of glaucoma and the crucial role of intraocular pressure (IOP) reduction in the management of the disease, understanding the immediate effects on retinal structure and function is essential. (2) Methods: This study aimed to assess the effects of preservati ...
Leto: 2024 Vir: Repozitorij Univerze v Ljubljani (RUL)
Št. zadetkov: 4
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