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Št. zadetkov: 2
High-sensitivity C-reactive protein and carotid intima media thickness as markers of subclinical inflammation and atherosclerosis in pediatric patients with hypercholesterolemia
Lana Blinc, Matej Mlinarič, Tadej Battelino, Urh Grošelj
Pregledni znanstveni članek
Oznake: familial hypercholesterolemia;polygenic hypercholesterolemia;inflammation;atherosclerosis;carotid intima media thickness;cIMT;C-reactive protein;hsCRP;
Hypercholesterolemia is a major cause of atherosclerosis development and premature cardiovascular disease (CVD). It leads to inflammation, which further accelerates atherosclerosis progression. Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by elevated serum LDL-c ...
Leto: 2020 Vir: Medicinska fakulteta (UL MF)
Probing Alzheimer's pathology
Luka Rejc, Damijan Knez, Gabriela Molina-Aguirre, Alba Espargaró, Jerneja Kladnik, Anže Meden, Lana Blinc, Matic Lozinšek, Ross D. Jansen-van Vuuren, Matic Rogan, Bruno Aleksander Martek, Jernej Mlakar, Ana Dremelj, Andrej Petrič, Stanislav Gobec, Mara Bresjanac, Janez Košmrlj
Izvirni znanstveni članek
Oznake: amyloid beta;fluorophore;solvatochromism;synthesis;photophysics;
Fluorescent probes are a powerful tool for imaging amyloid β (Aβ) plaques, the hallmark of Alzheimer’s disease (AD). Herein, we report the synthesis and comprehensive characterization of 21 novel probes as well as their optical properties and binding affinities to Aβ fibrils. One of these dyes, 1Ae, ...
Leto: 2024 Vir: Fakulteta za kemijo in kemijsko tehnologijo (UL FKKT)
Št. zadetkov: 2
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