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Št. zadetkov: 2
Tiered genotoxicity testing of enriched river water samples using zebrafish in vitro and in vivo models: a joint Danube Survey 4 case study
Margareta Kračun-Kolarević, Bojana Žegura, Katja Kološa, Jovana Jovanović Marić, Andrea Novaković, Peter Oswald, Martina Oswaldova, Jaroslav Slobodnik, Nikiforos Alygizakis, Momir Paunović
Izvirni znanstveni članek
Oznake: ZFL cell line;zebrafish embryos;cytotoxicity;genotoxicity;Danube River;
The increasing complexity of aquatic pollution, dominated by diverse and often uncharacterized chemical mixtures, challenges traditional monitoring approaches. In this study, we assessed the genotoxic potential of surface water samples collected during the Joint Danube Survey 4 (JDS4) using large-vo ...
Leto: 2026 Vir: Nacionalni inštitut za biologijo (NIB)
Influence of alkylthio and arylthio derivatives of tert-butylquinone on the induction of DNA damage in a human hepatocellular carcinoma cell line (HepG2)
Jelena Djordjević, Stoimir Kolarević, Jovana Jovanović Marić, Margareta Kračun-Kolarević, Bojana Žegura, Alja Štraser, Dušan M. Sladić, Irena Novaković, Branka Vuković-Gačić
Izvirni znanstveni članek
Oznake: TBQ derivatives;HepG2 cell line;comet assay;γH2AX assay;cell cycle analysis;cytotoxicity;
The aim of this study was to investigate the effects of tert-butylquinone (TBQ) and its alkylthio and arylthio derivatives on DNA in vitro, using acellular and cellular test systems. Direct interaction with DNA was studied using the plasmid pUC19. Cytotoxic (MTS assay) and genotoxic (comet assay and ...
Leto: 2024 Vir: Nacionalni inštitut za biologijo (NIB)
Št. zadetkov: 2
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