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Obscurin deficiency leads to compensated dilated cardiomyopathy and increased arrhythmias
Josè Manuel Pioner, Enrico Pierantozzi, Raffaele Coppini, Egidio Maria Rubino, Valentina Biasci, Giulia Vitale, Annunziatina Laurino, Lorenzo Santini, Marina Scardigli, Carlo Reggiani
Izvirni znanstveni članek
Oznake: sarcoplasmic reticulum;T-tubule alterations;E-C coupling;inotropic agents;arrhythmia;
Obscurin is a large muscle protein whose multiple functions include providing mechanical strength to the M-band and linking the sarcomere to the sarcoplasmic reticulum. Mutations in obscurin are linked to various forms of muscle diseases. This study compares cardiac function in a murine model of obs ...
Leto: 2025 Vir: Repozitorij Univerze na Primorskem (RUP)
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