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Št. zadetkov: 2
Microbial genetic variation impacts host eco-immunological strategies and microparasite fitness in Lyme borreliae-reptile system
Tristan A. Nowak, Carly Fernandes, Jill Malfetano, Erica Lasek-Nesselquist, Matthew Combs, Klemen Strle, Russell L. Burke, Yi-Pin Lin
Izvirni znanstveni članek
Oznake: Lyme disease;borrelia;tolerance;resistance;genetic variation;
Tolerance and resistance are two host eco-immunological strategies in response to microparasite invasion. In the strategy of “resistance”, host responses are induced to decrease microparasite replication while the “tolerance” strategy allows hosts coexistence with microparasites by minimizing respon ...
Leto: 2024 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Developing a durable, memory-driven, CspZ-targeting Lyme disease vaccine by rationale adjuvant selection
Miranda McCarty, Sergio A. Hernández, Jill Malfetano, Ana Carolina Leão, Maria Jose Villar, Xiuli Yang, Yi-Lin Chen, Jungsoon Lee, Zhuyun Liu, Ulrich Strych, Klemen Strle
Izvirni znanstveni članek
Oznake: Lyme disease;Lyme disease vaccine;immunization;
Rational adjuvant selection is a systematic approach based on adjuvant-mediated immunomodulation to identify safe vaccine regimens that enhance protective immunity. Transmitted through ticks and caused by the bacterium Borrelia burgdorferi (Bb), Lyme disease (LD) is the most common vector-borne dise ...
Leto: 2026 Vir: Digitalni repozitorij raziskovalnih organizacij Slovenije
Št. zadetkov: 2
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